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- W2949692939 abstract "An efficient diastereoselective approach for the preparation of novel substituted pyridines has been developed through a one-pot, four-component reaction of easily available aromatic aldehydes, malononitrile, and 6,8-dimethyl-2-hydroxy-4H-pyrimido[1,2-a]pyrimidine-4-one, in appropriate alcohols at reflux in the presence of diisopropylethylamine (DIPEA) as organic base catalyst. Unexpected products were obtained in high to excellent yields using a simple workup procedure. The products synthesized showed high diastereoselectivity, and the stereochemistry was confirmed by X-ray diffraction analysis." @default.
- W2949692939 created "2019-06-27" @default.
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- W2949692939 date "2016-10-01" @default.
- W2949692939 modified "2023-09-27" @default.
- W2949692939 title "ChemInform Abstract: An Unexpected Diastereoselective Synthesis of Novel Substituted Pyridines via One-Pot, Four-Component Reaction." @default.
- W2949692939 cites W2335849148 @default.
- W2949692939 doi "https://doi.org/10.1002/chin.201646054" @default.
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