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- W2949788261 abstract "The reaction of 4-mesyloxymethylazetidin-2-one derivatives 3 with ammonia and sodium methoxide was investigated. The two electrophilic centers of the substrate reactesuccessively, resulting in cleavage of the lactam bond and formation of a new aziridine ring. The resulting type 6 and 8 aziridinylacetic acid derivatives are related to the novel 2-(aziridin-2-yl)-3-phenylpropionic acid type carboxypeptidase A inhibitors and, as such, potential drug candidates." @default.
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- W2949788261 date "2006-01-01" @default.
- W2949788261 modified "2023-10-06" @default.
- W2949788261 title "Regioselective reactions of mesyloxymethylazetidinones with nucleophiles I. Cleavage of the azetidinone ring, azetidinone-aziridine ring transformations" @default.
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- W2949788261 doi "https://doi.org/10.1002/jhet.5570430114" @default.
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