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• W2949815521 abstract "A series of chalcones (1-9) and pyrazoles (10-18) was prepared to investigate their potential activity as Angiotensin I-Converting Enzyme (ACE) inhibitors. Their structures were verified by elemental analysis, UV, IR, MS, (1)H NMR, (13)C NMR, and 2D NMR experiments. Among tested compounds, chalcone 7 exerted the highest activity with an IC(50) value of 0.219 mM, while the most potent pyrazole was 15 (IC(50) value of 0.213 mM)." @default.
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• W2949815521 date "2010-03-01" @default.
• W2949815521 modified "2023-10-01" @default.
• W2949815521 title "The synthesis and Angiotensin Converting Enzyme (ACE) inhibitory activity of chalcones and their pyrazole derivatives" @default.
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• W2949815521 doi "https://doi.org/10.1016/j.bmcl.2010.01.113" @default.
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