Matches in SemOpenAlex for { <https://semopenalex.org/work/W2949832326> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2949832326 abstract "Direct Coupling Analysis (DCA) is a now widely used method to leverage statistical information from many similar biological systems to draw meaningful conclusions on each system separately. DCA has been applied with great success to sequences of homologous proteins, and also more recently to whole-genome population-wide sequencing data. We here argue that the use of DCA on the genome scale is contingent on fundamental issues of population genetics. DCA can be expected to yield meaningful results when a population is in the Quasi-Linkage Equilibrium (QLE) phase studied by Kimura and others, but not, for instance, in a phase of Clonal Competition. We discuss how the exponential (Potts model) distributions emerge in QLE, and compare couplings to correlations obtained in a study of about 3,000 genomes of the human pathogen Streptococcus pneumoniae." @default.
- W2949832326 created "2019-06-27" @default.
- W2949832326 creator A5008074295 @default.
- W2949832326 creator A5010412574 @default.
- W2949832326 creator A5047019776 @default.
- W2949832326 creator A5049436660 @default.
- W2949832326 creator A5066787180 @default.
- W2949832326 date "2018-08-10" @default.
- W2949832326 modified "2023-09-30" @default.
- W2949832326 title "DCA for genome-wide epistasis analysis: the statistical genetics perspective" @default.
- W2949832326 doi "https://doi.org/10.48550/arxiv.1808.03478" @default.
- W2949832326 hasPublicationYear "2018" @default.
- W2949832326 type Work @default.
- W2949832326 sameAs 2949832326 @default.
- W2949832326 citedByCount "0" @default.
- W2949832326 crossrefType "posted-content" @default.
- W2949832326 hasAuthorship W2949832326A5008074295 @default.
- W2949832326 hasAuthorship W2949832326A5010412574 @default.
- W2949832326 hasAuthorship W2949832326A5047019776 @default.
- W2949832326 hasAuthorship W2949832326A5049436660 @default.
- W2949832326 hasAuthorship W2949832326A5066787180 @default.
- W2949832326 hasBestOaLocation W29498323261 @default.
- W2949832326 hasConcept C104317684 @default.
- W2949832326 hasConcept C119857082 @default.
- W2949832326 hasConcept C12713177 @default.
- W2949832326 hasConcept C141231307 @default.
- W2949832326 hasConcept C144024400 @default.
- W2949832326 hasConcept C149923435 @default.
- W2949832326 hasConcept C153083717 @default.
- W2949832326 hasConcept C154945302 @default.
- W2949832326 hasConcept C2908647359 @default.
- W2949832326 hasConcept C41008148 @default.
- W2949832326 hasConcept C54355233 @default.
- W2949832326 hasConcept C61727976 @default.
- W2949832326 hasConcept C70721500 @default.
- W2949832326 hasConcept C78458016 @default.
- W2949832326 hasConcept C85721925 @default.
- W2949832326 hasConcept C86803240 @default.
- W2949832326 hasConceptScore W2949832326C104317684 @default.
- W2949832326 hasConceptScore W2949832326C119857082 @default.
- W2949832326 hasConceptScore W2949832326C12713177 @default.
- W2949832326 hasConceptScore W2949832326C141231307 @default.
- W2949832326 hasConceptScore W2949832326C144024400 @default.
- W2949832326 hasConceptScore W2949832326C149923435 @default.
- W2949832326 hasConceptScore W2949832326C153083717 @default.
- W2949832326 hasConceptScore W2949832326C154945302 @default.
- W2949832326 hasConceptScore W2949832326C2908647359 @default.
- W2949832326 hasConceptScore W2949832326C41008148 @default.
- W2949832326 hasConceptScore W2949832326C54355233 @default.
- W2949832326 hasConceptScore W2949832326C61727976 @default.
- W2949832326 hasConceptScore W2949832326C70721500 @default.
- W2949832326 hasConceptScore W2949832326C78458016 @default.
- W2949832326 hasConceptScore W2949832326C85721925 @default.
- W2949832326 hasConceptScore W2949832326C86803240 @default.
- W2949832326 hasLocation W29498323261 @default.
- W2949832326 hasOpenAccess W2949832326 @default.
- W2949832326 hasPrimaryLocation W29498323261 @default.
- W2949832326 hasRelatedWork W132072793 @default.
- W2949832326 hasRelatedWork W1847694100 @default.
- W2949832326 hasRelatedWork W1887326336 @default.
- W2949832326 hasRelatedWork W2002128513 @default.
- W2949832326 hasRelatedWork W2063853271 @default.
- W2949832326 hasRelatedWork W2116973997 @default.
- W2949832326 hasRelatedWork W2127102618 @default.
- W2949832326 hasRelatedWork W2531574073 @default.
- W2949832326 hasRelatedWork W325002145 @default.
- W2949832326 hasRelatedWork W2092874662 @default.
- W2949832326 isParatext "false" @default.
- W2949832326 isRetracted "false" @default.
- W2949832326 magId "2949832326" @default.
- W2949832326 workType "article" @default.