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- W2949893531 abstract "Background During the last 20 years, employment rates increased substantially in the German population and also in patients with arthritis [1]. Whether patients with primary Sjogren’s syndrome (pSS) also show this trend is less clear in the absence of new treatment options. Objectives To assess trends in treatment and outcomes in patients pSS, focusing on employment, hospitalization and medical treatment in the past two decades. Methods From 1996 to 2016, ∼300 patients with pSS were documented annually in the National Database of the German Collaborative Arthritis Centres. Data on treatment, physician assessment of disease activity, patient-reported outcomes, hospitalization and employment were collected and compared to patients with rheumatoid arthritis (RA), matched 1:1 for age, sex and disease duration for each calendar year. Results Patients with pSS (>90% female, age ∼44 years at disease onset, disease duration ∼10 years) were more frequently assessed to be in low disease activity in 2016 (93%) than in 1996 (62%, p Conclusion Overall, similar trends were observed for RA and pSS cohorts despite minor changes in pSS therapy. Work participation has improved significantly over two decades in pSS. A greater perception of pSS without systemic manifestations may have caused a shift towards less severely affected patient cohorts today. Reference [1] Mau W, Listing J, Huscher D, Zeidler H, Zink A. Employment across chronic inflammatory rheumatic diseases and comparison with the general population. J Rheumatol. 2005;32(4):721-8 Acknowledgement The database is funded by unconditional grants from the German Collaborative Arthritis Centres and from a consortium of 9 pharmaceutical companies to the German Academy for Continuing Medical Education in Rheumatology. Disclosure of Interests Johanna Callhoff: None declared, Katja Thiele: None declared, Thomas Dorner Grant/research support from: Eli Lilly, Janssen, Roche, UCB Pharma, Consultant for: Eli Lilly, Janssen, Roche, UCB Pharma, Speakers bureau: Eli Lilly, Janssen, Angela Zink Speakers bureau: Speakers fees from AbbVie, Janssen, Pfizer, Roche, Sanofi, Jorg Henes: None declared, Jutta Richter Grant/research support from: GlaxoSmithKline and UCB Pharma for performing the LuLa-study., Katinka Albrecht: None declared" @default.
- W2949893531 created "2019-06-27" @default.
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- W2949893531 date "2019-06-01" @default.
- W2949893531 modified "2023-09-30" @default.
- W2949893531 title "SAT0187 TRENDS IN EMPLOYMENT AND HOSPITALIZATION IN PATIENTS WITH SJÖGREN’S SYNDROME 1993–2016: RESULTS FROM THE GERMAN NATIONAL DATABASE" @default.
- W2949893531 doi "https://doi.org/10.1136/annrheumdis-2019-eular.1183" @default.
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