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• W2949905840 startingPage "2024" @default.
• W2949905840 abstract "A highly efficient one-pot [4 + 1]-annulation process for the asymmetric synthesis of densely functionalized pyrrolidine derivatives is described. The in situ generated syn-Mannich adduct obtained via proline catalysis acts as a four-atom component, and Corey’s sulfur ylide or ethyl bromoacetate acts as a one-atom carbon source to construct pyrrolidine units in a highly enantio- and diastereoselective manner." @default.
• W2949905840 created "2019-06-27" @default.
• W2949905840 creator A5008928380 @default.
• W2949905840 creator A5024935974 @default.
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• W2949905840 date "2015-01-27" @default.
• W2949905840 modified "2023-09-25" @default.
• W2949905840 title "Proline-Catalyzed Sequential <i>syn</i>-Mannich and [4 + 1]-Annulation Cascade Reactions To Form Densely Functionalized Pyrrolidines" @default.
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• W2949905840 doi "https://doi.org/10.1021/jo5028886" @default.
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