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- W2949943669 abstract "Abstract A growing body of research suggests that the mitochondrial genome (mtDNA) is important for temperature adaptation. In the yeast genus Saccharomyces , species have diverged in temperature tolerance, driving their use in high or low temperature fermentations. Here we experimentally test the role of mtDNA in temperature tolerance in synthetic and industrial hybrids ( Saccharomyces cerevisiae x Saccharomyces eubayanus , or Saccharomyces pastorianus ), which cold-brew lager beer. We find that the relative temperature tolerances of hybrids correspond to the parent donating mtDNA, allowing us to modulate lager strain temperature preferences. The strong influence of mitotype on the temperature tolerance of otherwise identical hybrid strains provides support for the mitochondrial climactic adaptation hypothesis in yeasts and demonstrates how mitotype has influenced the world's most commonly fermented beverage. One Sentence Summary Mitochondrial genome origin affects the temperature tolerance of synthetic and industrial lager-brewing yeast hybrids." @default.
- W2949943669 created "2019-06-27" @default.
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- W2949943669 date "2018-08-14" @default.
- W2949943669 modified "2023-10-16" @default.
- W2949943669 title "Mitochondrial DNA and temperature tolerance in lager yeasts" @default.
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- W2949943669 doi "https://doi.org/10.1101/391946" @default.
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