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- W2949944410 abstract "A straightforward and efficient synthetic route to a new class of glycosidase inhibitors containing an oxazole-2(3H)-thione moiety has been devised. The approach involves the formation of α-hydroxy ketones, which, after condensation with thiocyanic acid, leads to the formation of the heterocycle. By exploiting the ability of the nitrogen atom of oxazoline-2thione precursors to act as nucleophiles in intramolecular addition, castanospermine analogues could be readily prepared in good overall yields. Glycosidase inhibitory activity com" @default.
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- W2949944410 date "2014-05-22" @default.
- W2949944410 modified "2023-10-16" @default.
- W2949944410 title "ChemInform Abstract: N-Thiocarbonyl Iminosugars: Synthesis and Evaluation of Castanospermine Analogues Bearing Oxazole-2(3H)-thione Moieties." @default.
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- W2949944410 doi "https://doi.org/10.1002/chin.201423171" @default.
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