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- W2949956061 abstract "N-Methyl indole-2-hydrazide 1 was lithiated at the 3-position using t-BuLi in the presence of TMEDA in THF. The generated ortho-lithiated intermediate is reacted with a variety of electrophiles to give regioselectively 2,3-disubstituted indoles in good yields. The hydroxyhydrazides were converted to the corresponding lactones after oxidation with MnO2." @default.
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- W2949956061 date "2003-01-01" @default.
- W2949956061 modified "2023-09-25" @default.
- W2949956061 title "Directedortho-Lithiation of the 2-(N,N-Dimethylhydrazinecarbonyl)-1-methylindole. Efficient Preparation of Tricyclic Lactones" @default.
- W2949956061 doi "https://doi.org/10.1055/s-2003-36786" @default.
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