Matches in SemOpenAlex for { <https://semopenalex.org/work/W2950031306> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W2950031306 abstract "A challenging direct asymmetric hydrogenation of (E)-2-oxo-4-arylbut-3-enoic acids to give 2-hydroxy-4-arylbutanoic acids (85.4−91.8% ee) was achieved with a Ru catalyst based on SunPhos as the chiral ligand. Further investigation of the reaction revealed that partial isomerization of 2-hydroxy-4-arylbutenoic acids was involved in the hydrogenation process. Employing the reaction conditions to the hydrogenation of 2-oxo-4-phenylbutanoic acid resulted in better enantioselectivity (91.8% ee) and efficiency (TON = 2000, TOF = 200 h−1), which offers a useful method for the synthesis of a common intermediate for ACE inhibitors." @default.
- W2950031306 created "2019-06-27" @default.
- W2950031306 creator A5007573010 @default.
- W2950031306 creator A5026125673 @default.
- W2950031306 creator A5063288717 @default.
- W2950031306 creator A5078866836 @default.
- W2950031306 creator A5084756878 @default.
- W2950031306 date "2010-11-26" @default.
- W2950031306 modified "2023-09-27" @default.
- W2950031306 title "ChemInform Abstract: Direct Asymmetric Hydrogenation of 2-Oxo-4-arylbut-3-enoic Acids." @default.
- W2950031306 cites W2019067515 @default.
- W2950031306 doi "https://doi.org/10.1002/chin.201051050" @default.
- W2950031306 hasPublicationYear "2010" @default.
- W2950031306 type Work @default.
- W2950031306 sameAs 2950031306 @default.
- W2950031306 citedByCount "0" @default.
- W2950031306 crossrefType "journal-article" @default.
- W2950031306 hasAuthorship W2950031306A5007573010 @default.
- W2950031306 hasAuthorship W2950031306A5026125673 @default.
- W2950031306 hasAuthorship W2950031306A5063288717 @default.
- W2950031306 hasAuthorship W2950031306A5078866836 @default.
- W2950031306 hasAuthorship W2950031306A5084756878 @default.
- W2950031306 hasConcept C116569031 @default.
- W2950031306 hasConcept C126661725 @default.
- W2950031306 hasConcept C146686406 @default.
- W2950031306 hasConcept C155647269 @default.
- W2950031306 hasConcept C161790260 @default.
- W2950031306 hasConcept C170493617 @default.
- W2950031306 hasConcept C178790620 @default.
- W2950031306 hasConcept C185592680 @default.
- W2950031306 hasConcept C197356162 @default.
- W2950031306 hasConcept C21951064 @default.
- W2950031306 hasConcept C2992084085 @default.
- W2950031306 hasConcept C55493867 @default.
- W2950031306 hasConcept C67369912 @default.
- W2950031306 hasConcept C71240020 @default.
- W2950031306 hasConceptScore W2950031306C116569031 @default.
- W2950031306 hasConceptScore W2950031306C126661725 @default.
- W2950031306 hasConceptScore W2950031306C146686406 @default.
- W2950031306 hasConceptScore W2950031306C155647269 @default.
- W2950031306 hasConceptScore W2950031306C161790260 @default.
- W2950031306 hasConceptScore W2950031306C170493617 @default.
- W2950031306 hasConceptScore W2950031306C178790620 @default.
- W2950031306 hasConceptScore W2950031306C185592680 @default.
- W2950031306 hasConceptScore W2950031306C197356162 @default.
- W2950031306 hasConceptScore W2950031306C21951064 @default.
- W2950031306 hasConceptScore W2950031306C2992084085 @default.
- W2950031306 hasConceptScore W2950031306C55493867 @default.
- W2950031306 hasConceptScore W2950031306C67369912 @default.
- W2950031306 hasConceptScore W2950031306C71240020 @default.
- W2950031306 hasLocation W29500313061 @default.
- W2950031306 hasOpenAccess W2950031306 @default.
- W2950031306 hasPrimaryLocation W29500313061 @default.
- W2950031306 isParatext "false" @default.
- W2950031306 isRetracted "false" @default.
- W2950031306 magId "2950031306" @default.
- W2950031306 workType "article" @default.