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• W2950134277 abstract "Analysis of Hi-C data has shown that the genome can be divided into two compartments called A/B compartments. These compartments are cell-type specific and are associated with open and closed chromatin. We show that A/B compartments can be reliably estimated using epigenetic data from several different platforms, the Illumina 450k DNA methylation microarray, DNase hypersensitivity sequencing, single-cell ATAC sequencing and single-cell whole-genome bisulfite sequencing. We do this by exploiting the fact that the structure of long range correlations differs between open and closed compartments. This work makes A/B compartments readily available in a wide variety of cell types, including many human cancers." @default.
• W2950134277 created "2019-06-27" @default.
• W2950134277 creator A5053857063 @default.
• W2950134277 creator A5072443724 @default.
• W2950134277 date "2015-05-06" @default.
• W2950134277 modified "2023-09-24" @default.
• W2950134277 title "Reconstructing A/B compartments as revealed by Hi-C using long-range correlations in epigenetic data" @default.
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• W2950134277 doi "https://doi.org/10.1101/019000" @default.
• W2950134277 hasPublicationYear "2015" @default.
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