Matches in SemOpenAlex for { <https://semopenalex.org/work/W2950210234> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2950210234 abstract "A number of routes to 3-hydroxyiminodehydroquinate 4, one of the most potent inhibitors of type II dehydroquinase that is currently known, have been investigated. Methods based on the existing literature synthesis, i.e. oxime formation of a suitably C-4 and C-5 protected methyl 3-dehydroquinate derivative were initially studied. Benzoyl protection as in 11 did give the desired product but in low overall yield. An alternative BBA protection strategy starting with 7 was successful in generating a C-4/C-5 analogue of the desired oxime 4 in high yield. Further investigation revealed that it was unnecessary to protect the dehydroquinate precursor, hence the potassium salt corresponding to oxime 4 was simply synthesised as a single isomer from methyl dehydroquinate 10." @default.
- W2950210234 created "2019-06-27" @default.
- W2950210234 creator A5002890830 @default.
- W2950210234 creator A5033537928 @default.
- W2950210234 creator A5065780016 @default.
- W2950210234 date "2003-02-25" @default.
- W2950210234 modified "2023-09-27" @default.
- W2950210234 title "A Simple Method for the Preparation of 3-Hydroxyiminodehydroquinate, a Potent Inhibitor of Type II Dehydroquinase." @default.
- W2950210234 cites W2054123079 @default.
- W2950210234 doi "https://doi.org/10.1002/chin.200308187" @default.
- W2950210234 hasPublicationYear "2003" @default.
- W2950210234 type Work @default.
- W2950210234 sameAs 2950210234 @default.
- W2950210234 citedByCount "0" @default.
- W2950210234 crossrefType "journal-article" @default.
- W2950210234 hasAuthorship W2950210234A5002890830 @default.
- W2950210234 hasAuthorship W2950210234A5033537928 @default.
- W2950210234 hasAuthorship W2950210234A5065780016 @default.
- W2950210234 hasConcept C106159729 @default.
- W2950210234 hasConcept C111771559 @default.
- W2950210234 hasConcept C134121241 @default.
- W2950210234 hasConcept C162324750 @default.
- W2950210234 hasConcept C178790620 @default.
- W2950210234 hasConcept C185592680 @default.
- W2950210234 hasConcept C191897082 @default.
- W2950210234 hasConcept C192562407 @default.
- W2950210234 hasConcept C21951064 @default.
- W2950210234 hasConcept C2779648554 @default.
- W2950210234 hasConcept C517785266 @default.
- W2950210234 hasConcept C71240020 @default.
- W2950210234 hasConceptScore W2950210234C106159729 @default.
- W2950210234 hasConceptScore W2950210234C111771559 @default.
- W2950210234 hasConceptScore W2950210234C134121241 @default.
- W2950210234 hasConceptScore W2950210234C162324750 @default.
- W2950210234 hasConceptScore W2950210234C178790620 @default.
- W2950210234 hasConceptScore W2950210234C185592680 @default.
- W2950210234 hasConceptScore W2950210234C191897082 @default.
- W2950210234 hasConceptScore W2950210234C192562407 @default.
- W2950210234 hasConceptScore W2950210234C21951064 @default.
- W2950210234 hasConceptScore W2950210234C2779648554 @default.
- W2950210234 hasConceptScore W2950210234C517785266 @default.
- W2950210234 hasConceptScore W2950210234C71240020 @default.
- W2950210234 hasLocation W29502102341 @default.
- W2950210234 hasOpenAccess W2950210234 @default.
- W2950210234 hasPrimaryLocation W29502102341 @default.
- W2950210234 hasRelatedWork W2029852883 @default.
- W2950210234 hasRelatedWork W2099993997 @default.
- W2950210234 hasRelatedWork W2342090181 @default.
- W2950210234 hasRelatedWork W2402459354 @default.
- W2950210234 hasRelatedWork W2408601403 @default.
- W2950210234 hasRelatedWork W2949233514 @default.
- W2950210234 hasRelatedWork W2951756884 @default.
- W2950210234 hasRelatedWork W2952790522 @default.
- W2950210234 hasRelatedWork W2953026983 @default.
- W2950210234 hasRelatedWork W2106590688 @default.
- W2950210234 isParatext "false" @default.
- W2950210234 isRetracted "false" @default.
- W2950210234 magId "2950210234" @default.
- W2950210234 workType "article" @default.