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- W2950260040 abstract "This study was conducted to evaluate the renal protective effect of cardamom against experimentallyinducedgentamicin toxicity in rats. Forty adult male Westar albino rats were randomly grouped intofour groups (each of 10 rats). Rats in group (1) were orally administered saline (the vehicle) daily for 8consecutive days and severed as control group. Group 2: were given gentamicin (80 mg/kg. b.wt. i.p.)daily for 8 consecutive days. Group 3: were given gentamicin (80 mg/kg. b.wt. i.p.) daily for 8consecutive days, then cardamom extract (100 mg/kg. b.wt. p.o.) daily from 9th to 21th days. Group 4:were given gentamicin (80 mg/kg. b.wt. i.p.) daily for 8 consecutive days, then cardamom extract (200mg/kg. b.wt. p.o.) daily from 9th to 21th days. Gentamicin-treated rats showed significant renal damageas it increases creatinine, urea, glucose and total protein showed a significant decrease. While In groups(gentamicin + cardamom 100 mg/kg & gentamicin + cardamom 200 mg/kg), showed significantprotection to rats kidney from structural and functional changes associated with gentamicin. Gentamicinwhich induced nephrotoxicity can be prevented by co-administration with cardamom" @default.
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- W2950260040 date "2015-12-01" @default.
- W2950260040 modified "2023-10-06" @default.
- W2950260040 title "Renal protective effect of cardamom against nephrotoxicity induced by gentamicin in rats" @default.
- W2950260040 doi "https://doi.org/10.21608/bvmj.2015.31681" @default.
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