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- W2950320526 abstract "The design and synthesis of a novel scaffold for potent and selective PDE5 inhibitors are described. Compound 3a was more potent (PDE5 IC50=0.31 nM) and selective (>10,000-fold vs PDE1 and 160-fold selective vs PDE6) PDE5 inhibitor than sildenafil." @default.
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- W2950320526 date "2010-05-23" @default.
- W2950320526 modified "2023-09-23" @default.
- W2950320526 title "ChemInform Abstract: The Discovery of Novel, Potent and Selective PDE5 Inhibitors." @default.
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- W2950320526 doi "https://doi.org/10.1002/chin.200150145" @default.
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