FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2950340163> ?p ?o ?g. }

• W2950340163 endingPage "732" @default.
• W2950340163 startingPage "721" @default.
• W2950340163 abstract "How likely is it that a population escapes extinction through adaptive evolution? The answer to this question is of great relevance in conservation biology, where we aim at species' rescue and the maintenance of biodiversity, and in agriculture and medicine, where we seek to hamper the emergence of pesticide or drug resistance. By reshuffling the genome, recombination has two antagonistic effects on the probability of evolutionary rescue: it generates and it breaks up favorable gene combinations. Which of the two effects prevails depends on the fitness effects of mutations and on the impact of stochasticity on the allele frequencies. In this article, we analyze a mathematical model for rescue after a sudden environmental change when adaptation is contingent on mutations at two loci. The analysis reveals a complex nonlinear dependence of population survival on recombination. We moreover find that, counterintuitively, a fast eradication of the wild type can promote rescue in the presence of recombination. The model also shows that two-step rescue is not unlikely to happen and can even be more likely than single-step rescue (where adaptation relies on a single mutation), depending on the circumstances." @default.
• W2950340163 created "2019-06-27" @default.
• W2950340163 creator A5032789220 @default.
• W2950340163 creator A5037864316 @default.
• W2950340163 date "2015-12-01" @default.
• W2950340163 modified "2023-09-26" @default.
• W2950340163 title "The Role of Recombination in Evolutionary Rescue" @default.
• W2950340163 cites W1562407349 @default.
• W2950340163 cites W1935972705 @default.
• W2950340163 cites W1966522287 @default.
• W2950340163 cites W1969445455 @default.
• W2950340163 cites W1971557989 @default.
• W2950340163 cites W1977253473 @default.
• W2950340163 cites W1981214207 @default.
• W2950340163 cites W1982985222 @default.
• W2950340163 cites W1991747094 @default.
• W2950340163 cites W1992586746 @default.
• W2950340163 cites W1995176570 @default.
• W2950340163 cites W1995865334 @default.
• W2950340163 cites W2001369581 @default.
• W2950340163 cites W2004862733 @default.
• W2950340163 cites W2007737718 @default.
• W2950340163 cites W2023690349 @default.
• W2950340163 cites W2028372309 @default.
• W2950340163 cites W2035998101 @default.
• W2950340163 cites W2048513931 @default.
• W2950340163 cites W2052381091 @default.
• W2950340163 cites W2053063524 @default.
• W2950340163 cites W2053125140 @default.
• W2950340163 cites W2059238811 @default.
• W2950340163 cites W2072982091 @default.
• W2950340163 cites W2074229654 @default.
• W2950340163 cites W2078447116 @default.
• W2950340163 cites W2079752712 @default.
• W2950340163 cites W2080647790 @default.
• W2950340163 cites W2080777238 @default.
• W2950340163 cites W2082929763 @default.
• W2950340163 cites W2083598124 @default.
• W2950340163 cites W2086901644 @default.
• W2950340163 cites W2087487913 @default.
• W2950340163 cites W2087875068 @default.
• W2950340163 cites W2097958122 @default.
• W2950340163 cites W2099043018 @default.
• W2950340163 cites W2099449559 @default.
• W2950340163 cites W2102260112 @default.
• W2950340163 cites W2106756635 @default.
• W2950340163 cites W2107990492 @default.
• W2950340163 cites W2109947766 @default.
• W2950340163 cites W2110761360 @default.
• W2950340163 cites W2135021279 @default.
• W2950340163 cites W2142812124 @default.
• W2950340163 cites W2148134634 @default.
• W2950340163 cites W2158673360 @default.
• W2950340163 cites W2160272005 @default.
• W2950340163 cites W2162632787 @default.
• W2950340163 cites W2170986922 @default.
• W2950340163 cites W2267436601 @default.
• W2950340163 cites W2321397969 @default.
• W2950340163 cites W4299503683 @default.
• W2950340163 doi "https://doi.org/10.1534/genetics.115.180299" @default.
• W2950340163 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4788245" @default.
• W2950340163 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26627842" @default.
• W2950340163 hasPublicationYear "2015" @default.
• W2950340163 type Work @default.
• W2950340163 sameAs 2950340163 @default.
• W2950340163 citedByCount "45" @default.
• W2950340163 countsByYear W29503401632016 @default.
• W2950340163 countsByYear W29503401632017 @default.
• W2950340163 countsByYear W29503401632018 @default.
• W2950340163 countsByYear W29503401632019 @default.
• W2950340163 countsByYear W29503401632020 @default.
• W2950340163 countsByYear W29503401632021 @default.
• W2950340163 countsByYear W29503401632022 @default.
• W2950340163 crossrefType "journal-article" @default.
• W2950340163 hasAuthorship W2950340163A5032789220 @default.
• W2950340163 hasAuthorship W2950340163A5037864316 @default.
• W2950340163 hasBestOaLocation W29503401631 @default.
• W2950340163 hasConcept C101991246 @default.
• W2950340163 hasConcept C104317684 @default.
• W2950340163 hasConcept C139807058 @default.
• W2950340163 hasConcept C144024400 @default.
• W2950340163 hasConcept C149923435 @default.
• W2950340163 hasConcept C151730666 @default.
• W2950340163 hasConcept C156695909 @default.
• W2950340163 hasConcept C169760540 @default.
• W2950340163 hasConcept C180754005 @default.
• W2950340163 hasConcept C2908647359 @default.
• W2950340163 hasConcept C2910387474 @default.
• W2950340163 hasConcept C2992278830 @default.
• W2950340163 hasConcept C501734568 @default.
• W2950340163 hasConcept C54355233 @default.
• W2950340163 hasConcept C78458016 @default.
• W2950340163 hasConcept C86803240 @default.
• W2950340163 hasConceptScore W2950340163C101991246 @default.
• W2950340163 hasConceptScore W2950340163C104317684 @default.
• W2950340163 hasConceptScore W2950340163C139807058 @default.
• W2950340163 hasConceptScore W2950340163C144024400 @default.
• W2950340163 hasConceptScore W2950340163C149923435 @default.

• next