Matches in SemOpenAlex for { <https://semopenalex.org/work/W2950368466> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2950368466 abstract "We report here the synthesis of nucleoside and oligonucleotide analogs containing selenium, which serves as an anomalous scattering center to enable MAD phase determination in nucleotide X-ray crystallography. We have developed a phase transfer approach to introduce the selenium functionality in A, C, G, T, and U nucleosides at 5′-positions. In the incorporation of the selenium functionality, the leaving groups (bromide, mesyl, and tosyl) were readily displaced by sodium selenide, sodium diselenide, and sodium methyl selenide with yields higher than 90%. Selenium-derivatized oligonucleotides have been synthesized via phosphoramidite chemistry." @default.
- W2950368466 created "2019-06-27" @default.
- W2950368466 creator A5059821307 @default.
- W2950368466 creator A5061380390 @default.
- W2950368466 creator A5065200215 @default.
- W2950368466 creator A5070305427 @default.
- W2950368466 date "2010-05-22" @default.
- W2950368466 modified "2023-09-24" @default.
- W2950368466 title "ChemInform Abstract: Synthesis of Selenium-Derivatized Nucleosides and Oligonucleotides for X-Ray Crystallography." @default.
- W2950368466 cites W2034131760 @default.
- W2950368466 doi "https://doi.org/10.1002/chin.200208251" @default.
- W2950368466 hasPublicationYear "2010" @default.
- W2950368466 type Work @default.
- W2950368466 sameAs 2950368466 @default.
- W2950368466 citedByCount "0" @default.
- W2950368466 crossrefType "journal-article" @default.
- W2950368466 hasAuthorship W2950368466A5059821307 @default.
- W2950368466 hasAuthorship W2950368466A5061380390 @default.
- W2950368466 hasAuthorship W2950368466A5065200215 @default.
- W2950368466 hasAuthorship W2950368466A5070305427 @default.
- W2950368466 hasConcept C104317684 @default.
- W2950368466 hasConcept C129312508 @default.
- W2950368466 hasConcept C178790620 @default.
- W2950368466 hasConcept C185592680 @default.
- W2950368466 hasConcept C21951064 @default.
- W2950368466 hasConcept C2776043002 @default.
- W2950368466 hasConcept C2776543447 @default.
- W2950368466 hasConcept C2777016790 @default.
- W2950368466 hasConcept C2779680806 @default.
- W2950368466 hasConcept C512185932 @default.
- W2950368466 hasConcept C552990157 @default.
- W2950368466 hasConcept C553756173 @default.
- W2950368466 hasConcept C55493867 @default.
- W2950368466 hasConcept C71240020 @default.
- W2950368466 hasConceptScore W2950368466C104317684 @default.
- W2950368466 hasConceptScore W2950368466C129312508 @default.
- W2950368466 hasConceptScore W2950368466C178790620 @default.
- W2950368466 hasConceptScore W2950368466C185592680 @default.
- W2950368466 hasConceptScore W2950368466C21951064 @default.
- W2950368466 hasConceptScore W2950368466C2776043002 @default.
- W2950368466 hasConceptScore W2950368466C2776543447 @default.
- W2950368466 hasConceptScore W2950368466C2777016790 @default.
- W2950368466 hasConceptScore W2950368466C2779680806 @default.
- W2950368466 hasConceptScore W2950368466C512185932 @default.
- W2950368466 hasConceptScore W2950368466C552990157 @default.
- W2950368466 hasConceptScore W2950368466C553756173 @default.
- W2950368466 hasConceptScore W2950368466C55493867 @default.
- W2950368466 hasConceptScore W2950368466C71240020 @default.
- W2950368466 hasLocation W29503684661 @default.
- W2950368466 hasOpenAccess W2950368466 @default.
- W2950368466 hasPrimaryLocation W29503684661 @default.
- W2950368466 hasRelatedWork W1549343939 @default.
- W2950368466 hasRelatedWork W1574745030 @default.
- W2950368466 hasRelatedWork W1592222916 @default.
- W2950368466 hasRelatedWork W1665852824 @default.
- W2950368466 hasRelatedWork W1964392594 @default.
- W2950368466 hasRelatedWork W1979517043 @default.
- W2950368466 hasRelatedWork W1991248687 @default.
- W2950368466 hasRelatedWork W1998144272 @default.
- W2950368466 hasRelatedWork W2010752894 @default.
- W2950368466 hasRelatedWork W2034131760 @default.
- W2950368466 hasRelatedWork W2076840783 @default.
- W2950368466 hasRelatedWork W2077530843 @default.
- W2950368466 hasRelatedWork W2101999524 @default.
- W2950368466 hasRelatedWork W2128997110 @default.
- W2950368466 hasRelatedWork W2133292992 @default.
- W2950368466 hasRelatedWork W2146250585 @default.
- W2950368466 hasRelatedWork W2152511840 @default.
- W2950368466 hasRelatedWork W2160501894 @default.
- W2950368466 hasRelatedWork W2770605261 @default.
- W2950368466 hasRelatedWork W2951704271 @default.
- W2950368466 isParatext "false" @default.
- W2950368466 isRetracted "false" @default.
- W2950368466 magId "2950368466" @default.
- W2950368466 workType "article" @default.