Matches in SemOpenAlex for { <https://semopenalex.org/work/W2950458873> ?p ?o ?g. }
- W2950458873 endingPage "11481" @default.
- W2950458873 startingPage "11476" @default.
- W2950458873 abstract "Significance Chondrodystrophy, characterized by short limbs and intervertebral disc disease (IVDD), is a common phenotype in many of the most popular dog breeds, including the dachshund, beagle, and French bulldog. Here, we report the identification of a FGF4 retrogene insertion on chromosome 12, the second FGF4 retrogene reported in the dog, as responsible for chondrodystrophy and IVDD. Identification of the causative mutation for IVDD will impact an incredibly large proportion of the dog population and provides a model for IVDD in humans, as FGF-associated mutations are responsible for IVDD and short stature in human achondroplasia. This is a report of a second retrogene copy of the same parental gene, each causing complementary disease phenotypes in a mammalian species." @default.
- W2950458873 created "2019-06-27" @default.
- W2950458873 creator A5003998207 @default.
- W2950458873 creator A5020799928 @default.
- W2950458873 creator A5026946585 @default.
- W2950458873 creator A5031992432 @default.
- W2950458873 creator A5036229691 @default.
- W2950458873 creator A5041305349 @default.
- W2950458873 creator A5051716081 @default.
- W2950458873 creator A5055687069 @default.
- W2950458873 creator A5074904800 @default.
- W2950458873 creator A5080745721 @default.
- W2950458873 creator A5082187883 @default.
- W2950458873 creator A5083034928 @default.
- W2950458873 creator A5083483972 @default.
- W2950458873 creator A5091325048 @default.
- W2950458873 date "2017-10-11" @default.
- W2950458873 modified "2023-10-17" @default.
- W2950458873 title "<i>FGF4</i> retrogene on CFA12 is responsible for chondrodystrophy and intervertebral disc disease in dogs" @default.
- W2950458873 cites W1531710418 @default.
- W2950458873 cites W1659989665 @default.
- W2950458873 cites W1936280563 @default.
- W2950458873 cites W1951882906 @default.
- W2950458873 cites W1955467086 @default.
- W2950458873 cites W1965360106 @default.
- W2950458873 cites W1967485093 @default.
- W2950458873 cites W1977491069 @default.
- W2950458873 cites W1981152217 @default.
- W2950458873 cites W1981244256 @default.
- W2950458873 cites W1981856729 @default.
- W2950458873 cites W1989335612 @default.
- W2950458873 cites W1996092973 @default.
- W2950458873 cites W2000853250 @default.
- W2950458873 cites W2002320944 @default.
- W2950458873 cites W2007307254 @default.
- W2950458873 cites W2007569961 @default.
- W2950458873 cites W2016499348 @default.
- W2950458873 cites W2019476547 @default.
- W2950458873 cites W2021926661 @default.
- W2950458873 cites W2023397910 @default.
- W2950458873 cites W2036851890 @default.
- W2950458873 cites W2040741651 @default.
- W2950458873 cites W2042545863 @default.
- W2950458873 cites W2050249780 @default.
- W2950458873 cites W2072169337 @default.
- W2950458873 cites W2075322700 @default.
- W2950458873 cites W2075583075 @default.
- W2950458873 cites W2079047427 @default.
- W2950458873 cites W2085338873 @default.
- W2950458873 cites W2087681059 @default.
- W2950458873 cites W2093063059 @default.
- W2950458873 cites W2105179612 @default.
- W2950458873 cites W2110873651 @default.
- W2950458873 cites W2117119520 @default.
- W2950458873 cites W2118971517 @default.
- W2950458873 cites W2122893035 @default.
- W2950458873 cites W2130978406 @default.
- W2950458873 cites W2133436002 @default.
- W2950458873 cites W2139727029 @default.
- W2950458873 cites W2142846383 @default.
- W2950458873 cites W2159252607 @default.
- W2950458873 cites W2161395384 @default.
- W2950458873 cites W2165881979 @default.
- W2950458873 cites W2263703262 @default.
- W2950458873 cites W2284159252 @default.
- W2950458873 cites W2319017331 @default.
- W2950458873 cites W2394753657 @default.
- W2950458873 cites W2466886369 @default.
- W2950458873 cites W2606562533 @default.
- W2950458873 cites W4206553255 @default.
- W2950458873 cites W4248804829 @default.
- W2950458873 cites W90972230 @default.
- W2950458873 doi "https://doi.org/10.1073/pnas.1709082114" @default.
- W2950458873 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5664524" @default.
- W2950458873 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29073074" @default.
- W2950458873 hasPublicationYear "2017" @default.
- W2950458873 type Work @default.
- W2950458873 sameAs 2950458873 @default.
- W2950458873 citedByCount "83" @default.
- W2950458873 countsByYear W29504588732018 @default.
- W2950458873 countsByYear W29504588732019 @default.
- W2950458873 countsByYear W29504588732020 @default.
- W2950458873 countsByYear W29504588732021 @default.
- W2950458873 countsByYear W29504588732022 @default.
- W2950458873 countsByYear W29504588732023 @default.
- W2950458873 crossrefType "journal-article" @default.
- W2950458873 hasAuthorship W2950458873A5003998207 @default.
- W2950458873 hasAuthorship W2950458873A5020799928 @default.
- W2950458873 hasAuthorship W2950458873A5026946585 @default.
- W2950458873 hasAuthorship W2950458873A5031992432 @default.
- W2950458873 hasAuthorship W2950458873A5036229691 @default.
- W2950458873 hasAuthorship W2950458873A5041305349 @default.
- W2950458873 hasAuthorship W2950458873A5051716081 @default.
- W2950458873 hasAuthorship W2950458873A5055687069 @default.
- W2950458873 hasAuthorship W2950458873A5074904800 @default.
- W2950458873 hasAuthorship W2950458873A5080745721 @default.
- W2950458873 hasAuthorship W2950458873A5082187883 @default.
- W2950458873 hasAuthorship W2950458873A5083034928 @default.