FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2950470569> ?p ?o ?g. }

• W2950470569 endingPage "e0218659" @default.
• W2950470569 startingPage "e0218659" @default.
• W2950470569 abstract "We studied the effect of derrone (DR), one of the major compounds of unripe fruits of Cudrania tricuspidata, on cancer cell death. DR inhibited cell growth of various cancer cells, and that was partially associated with apoptosis in A549 cells. DR showed the autophagic features, such as the conversion of LC3-I to LC3-II, the formation of autophagosome and the downregulation of SQSTM1/p62 (p62). The treatment of autophagy inhibitor reversed DR-mediated cell death, suggesting that DR induces autophagic cell death. The increase of cytoplasmic Ca2+ and ROS by DR treatment significantly influences the formation of autophagosomes; however, only ROS scavengers significantly rescued the reduced cell viability. Additional results revealed that treatment of DR induces sustained phosphorylation of ERK and the inhibition of ERK phosphorylation using U0126 (ERK inhibitor) markedly attenuated DR-induced cell death. Overall, these results suggest that DR induces autophagic cell death through intracellular ROS and sustained ERK phosphorylation in A549 cells." @default.
• W2950470569 created "2019-06-27" @default.
• W2950470569 creator A5013859631 @default.
• W2950470569 creator A5023604242 @default.
• W2950470569 creator A5035173241 @default.
• W2950470569 creator A5042917835 @default.
• W2950470569 creator A5069476961 @default.
• W2950470569 creator A5070888329 @default.
• W2950470569 creator A5071671007 @default.
• W2950470569 creator A5073629644 @default.
• W2950470569 date "2019-06-19" @default.
• W2950470569 modified "2023-09-26" @default.
• W2950470569 title "Derrone induces autophagic cell death through induction of ROS and ERK in A549 cells" @default.
• W2950470569 cites W1521411817 @default.
• W2950470569 cites W1523693806 @default.
• W2950470569 cites W1784425676 @default.
• W2950470569 cites W1969898574 @default.
• W2950470569 cites W1980728700 @default.
• W2950470569 cites W1987695408 @default.
• W2950470569 cites W1987769185 @default.
• W2950470569 cites W1988840598 @default.
• W2950470569 cites W1990414934 @default.
• W2950470569 cites W1995726427 @default.
• W2950470569 cites W2003911732 @default.
• W2950470569 cites W2008347936 @default.
• W2950470569 cites W2008757142 @default.
• W2950470569 cites W2019291522 @default.
• W2950470569 cites W2019576484 @default.
• W2950470569 cites W2024650854 @default.
• W2950470569 cites W2027867588 @default.
• W2950470569 cites W2032830665 @default.
• W2950470569 cites W2035339329 @default.
• W2950470569 cites W2054841768 @default.
• W2950470569 cites W2055811314 @default.
• W2950470569 cites W2065126270 @default.
• W2950470569 cites W2066687597 @default.
• W2950470569 cites W2067659910 @default.
• W2950470569 cites W2078893058 @default.
• W2950470569 cites W2079279840 @default.
• W2950470569 cites W2081084980 @default.
• W2950470569 cites W2082933942 @default.
• W2950470569 cites W2094635065 @default.
• W2950470569 cites W2124105006 @default.
• W2950470569 cites W2138145250 @default.
• W2950470569 cites W2142416302 @default.
• W2950470569 cites W2149388384 @default.
• W2950470569 cites W2157320227 @default.
• W2950470569 cites W2173846903 @default.
• W2950470569 cites W2186706269 @default.
• W2950470569 cites W2324857722 @default.
• W2950470569 cites W2591669929 @default.
• W2950470569 cites W2594721637 @default.
• W2950470569 cites W2594980227 @default.
• W2950470569 cites W2625490265 @default.
• W2950470569 cites W2730689048 @default.
• W2950470569 cites W2738996050 @default.
• W2950470569 cites W2754437817 @default.
• W2950470569 cites W2794844962 @default.
• W2950470569 cites W2981211573 @default.
• W2950470569 cites W3195247524 @default.
• W2950470569 cites W4234236664 @default.
• W2950470569 cites W963613765 @default.
• W2950470569 doi "https://doi.org/10.1371/journal.pone.0218659" @default.
• W2950470569 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6583947" @default.
• W2950470569 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31216334" @default.
• W2950470569 hasPublicationYear "2019" @default.
• W2950470569 type Work @default.
• W2950470569 sameAs 2950470569 @default.
• W2950470569 citedByCount "7" @default.
• W2950470569 countsByYear W29504705692021 @default.
• W2950470569 countsByYear W29504705692022 @default.
• W2950470569 countsByYear W29504705692023 @default.
• W2950470569 crossrefType "journal-article" @default.
• W2950470569 hasAuthorship W2950470569A5013859631 @default.
• W2950470569 hasAuthorship W2950470569A5023604242 @default.
• W2950470569 hasAuthorship W2950470569A5035173241 @default.
• W2950470569 hasAuthorship W2950470569A5042917835 @default.
• W2950470569 hasAuthorship W2950470569A5069476961 @default.
• W2950470569 hasAuthorship W2950470569A5070888329 @default.
• W2950470569 hasAuthorship W2950470569A5071671007 @default.
• W2950470569 hasAuthorship W2950470569A5073629644 @default.
• W2950470569 hasBestOaLocation W29504705691 @default.
• W2950470569 hasConcept C11960822 @default.
• W2950470569 hasConcept C121608353 @default.
• W2950470569 hasConcept C184235292 @default.
• W2950470569 hasConcept C185592680 @default.
• W2950470569 hasConcept C190283241 @default.
• W2950470569 hasConcept C203522944 @default.
• W2950470569 hasConcept C31573885 @default.
• W2950470569 hasConcept C502942594 @default.
• W2950470569 hasConcept C53227056 @default.
• W2950470569 hasConcept C54355233 @default.
• W2950470569 hasConcept C55493867 @default.
• W2950470569 hasConcept C57074206 @default.
• W2950470569 hasConcept C62112901 @default.
• W2950470569 hasConcept C79879829 @default.
• W2950470569 hasConcept C81729549 @default.
• W2950470569 hasConcept C86803240 @default.

• next