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- W2950496636 abstract "[formula: see text] Starting with the proteinogenic amino acid (S)-glutamate, a general method for the synthesis of 3-(piperazin-2-yl)propionic acid esters 7 with various substituents at N-4 of the piperazine ring system is presented. An intramolecular ester condensation of 7 is the key step in the formation of the 6,8-diazabicyclo[3.2.2]nonane derivatives 8-10, which are of interest as conformationally restricted piperazines." @default.
- W2950496636 created "2019-06-27" @default.
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- W2950496636 date "2000-03-31" @default.
- W2950496636 modified "2023-09-27" @default.
- W2950496636 title "Synthesis of 6,8-Diazabicyclo[3.2.2]nonanes: Conformationally Restricted Piperazine Derivatives" @default.
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- W2950496636 doi "https://doi.org/10.1021/ol990393a" @default.
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