FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2950500026> ?p ?o ?g. }

• W2950500026 endingPage "584.e1" @default.
• W2950500026 startingPage "579" @default.
• W2950500026 abstract "BackgroundApproximately 50% of patients with polycythemia vera (PV) have PV-related symptoms at diagnosis; these symptoms might develop or worsen with time. Symptoms have been shown to negatively affect quality of life and interfere with daily activities. To our knowledge, an analysis to evaluate the relationship between blood count control and symptoms has not been published.Patients and MethodsThe Prospective Observational Study of Patients with Polycythemia Vera in US Clinical Practices (REVEAL; NCT02252159) is a multicenter, noninterventional, nonrandomized prospective observational study of patients with PV in the United States. Patients included were required to have a complete blood count result within 30 days before completing the at-enrollment Myeloproliferative Neoplasm Self-Assessment Form Total Symptom Score (MPN-SAF TSS). Symptom severity was compared between those who had blood count control versus those who did not.ResultsAt the time of enrollment, 1714 patients (94.5%) were being managed with cytoreductive therapy; 468 patients (25.8%) had complete hematologic remission (CHR), 1614 patients (89.0%) had ≥1 controlled blood count, and 1122 patients (61.9%) had ≥2 controlled blood counts. Mean MPN-SAF TSSs were similar across patients in different blood count control groups. Fatigue was the most frequently reported symptom. The severity of individual symptoms, except those of pruritus and night sweats, was not affected by CHR or the number of blood counts that were controlled.ConclusionSymptom burden in patients with PV can persist despite control of blood counts, which suggests some discordance between laboratory values and symptom burden. Consequently, regular monitoring of symptom burden should be factored into the assessment of disease control." @default.
• W2950500026 created "2019-06-27" @default.
• W2950500026 creator A5014139712 @default.
• W2950500026 creator A5022887326 @default.
• W2950500026 creator A5023728016 @default.
• W2950500026 creator A5027588079 @default.
• W2950500026 creator A5039013983 @default.
• W2950500026 creator A5039057642 @default.
• W2950500026 creator A5042176968 @default.
• W2950500026 creator A5049400849 @default.
• W2950500026 creator A5061916244 @default.
• W2950500026 creator A5075641618 @default.
• W2950500026 creator A5091492816 @default.
• W2950500026 date "2019-09-01" @default.
• W2950500026 modified "2023-10-10" @default.
• W2950500026 title "Symptom Burden and Blood Counts in Patients With Polycythemia Vera in the United States: An Analysis From the REVEAL Study" @default.
• W2950500026 cites W1966089852 @default.
• W2950500026 cites W1968468753 @default.
• W2950500026 cites W1979832242 @default.
• W2950500026 cites W1983819402 @default.
• W2950500026 cites W1990503714 @default.
• W2950500026 cites W1991495650 @default.
• W2950500026 cites W1996502308 @default.
• W2950500026 cites W2005328779 @default.
• W2950500026 cites W2017469038 @default.
• W2950500026 cites W2027789412 @default.
• W2950500026 cites W2068493370 @default.
• W2950500026 cites W2070883318 @default.
• W2950500026 cites W2072881492 @default.
• W2950500026 cites W2083764571 @default.
• W2950500026 cites W2090819633 @default.
• W2950500026 cites W2097694060 @default.
• W2950500026 cites W2112316414 @default.
• W2950500026 cites W2134290384 @default.
• W2950500026 cites W2134919790 @default.
• W2950500026 cites W2141249732 @default.
• W2950500026 cites W2144664431 @default.
• W2950500026 cites W2154754390 @default.
• W2950500026 cites W2178961707 @default.
• W2950500026 cites W2287599500 @default.
• W2950500026 cites W2287857102 @default.
• W2950500026 cites W2290101321 @default.
• W2950500026 cites W2339658711 @default.
• W2950500026 cites W2565781760 @default.
• W2950500026 cites W2744846745 @default.
• W2950500026 cites W2790003237 @default.
• W2950500026 cites W942930643 @default.
• W2950500026 doi "https://doi.org/10.1016/j.clml.2019.06.001" @default.
• W2950500026 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8148986" @default.
• W2950500026 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31303457" @default.
• W2950500026 hasPublicationYear "2019" @default.
• W2950500026 type Work @default.
• W2950500026 sameAs 2950500026 @default.
• W2950500026 citedByCount "13" @default.
• W2950500026 countsByYear W29505000262020 @default.
• W2950500026 countsByYear W29505000262021 @default.
• W2950500026 countsByYear W29505000262022 @default.
• W2950500026 countsByYear W29505000262023 @default.
• W2950500026 crossrefType "journal-article" @default.
• W2950500026 hasAuthorship W2950500026A5014139712 @default.
• W2950500026 hasAuthorship W2950500026A5022887326 @default.
• W2950500026 hasAuthorship W2950500026A5023728016 @default.
• W2950500026 hasAuthorship W2950500026A5027588079 @default.
• W2950500026 hasAuthorship W2950500026A5039013983 @default.
• W2950500026 hasAuthorship W2950500026A5039057642 @default.
• W2950500026 hasAuthorship W2950500026A5042176968 @default.
• W2950500026 hasAuthorship W2950500026A5049400849 @default.
• W2950500026 hasAuthorship W2950500026A5061916244 @default.
• W2950500026 hasAuthorship W2950500026A5075641618 @default.
• W2950500026 hasAuthorship W2950500026A5091492816 @default.
• W2950500026 hasBestOaLocation W29505000261 @default.
• W2950500026 hasConcept C126322002 @default.
• W2950500026 hasConcept C159110408 @default.
• W2950500026 hasConcept C188816634 @default.
• W2950500026 hasConcept C23131810 @default.
• W2950500026 hasConcept C2776376844 @default.
• W2950500026 hasConcept C2778837598 @default.
• W2950500026 hasConcept C2779951463 @default.
• W2950500026 hasConcept C2780007613 @default.
• W2950500026 hasConcept C2780076729 @default.
• W2950500026 hasConcept C2781107747 @default.
• W2950500026 hasConcept C3019917304 @default.
• W2950500026 hasConcept C71924100 @default.
• W2950500026 hasConceptScore W2950500026C126322002 @default.
• W2950500026 hasConceptScore W2950500026C159110408 @default.
• W2950500026 hasConceptScore W2950500026C188816634 @default.
• W2950500026 hasConceptScore W2950500026C23131810 @default.
• W2950500026 hasConceptScore W2950500026C2776376844 @default.
• W2950500026 hasConceptScore W2950500026C2778837598 @default.
• W2950500026 hasConceptScore W2950500026C2779951463 @default.
• W2950500026 hasConceptScore W2950500026C2780007613 @default.
• W2950500026 hasConceptScore W2950500026C2780076729 @default.
• W2950500026 hasConceptScore W2950500026C2781107747 @default.
• W2950500026 hasConceptScore W2950500026C3019917304 @default.
• W2950500026 hasConceptScore W2950500026C71924100 @default.
• W2950500026 hasFunder F4320309052 @default.
• W2950500026 hasFunder F4320309086 @default.
• W2950500026 hasFunder F4320313971 @default.

• next