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- W2950576313 abstract "The highly enantioselective synthesis of 2,2-difluoro-3-hydroxycarboxylates has been achieved by hydrogenating 2,2-difluoro-3-oxocarboxylates in the presence of chiral rhodium-(amidephosphine-phosphinite) complexes. Ethyl 4,4,4-trifluoroacetoacetate can be successfully transformed into the enantiomerically enriched 4,4,4-trifluoro-3-hydroxybutanoate in the same manner." @default.
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- W2950576313 date "2000-12-01" @default.
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- W2950576313 title "Enantioselective synthesis of 2,2-difluoro-3-hydroxycarboxylates by rhodium-catalyzed hydrogenation" @default.
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- W2950576313 doi "https://doi.org/10.1016/s0040-4039(00)01744-5" @default.
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