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- W2950577559 abstract "Abstract The procedures used today for oligo-DNA synthesis are reviewed. The main applications of oligonucleotides in biological studies, the protecting group chemistry, the coupling procedures, and the methods for isolating and characterizing products are described. Contents . Introduction. Uses of DNA Oligomers. Established methods of synthesis and general strategies. Types of solid supports. Protection of the nucleic bases. Thymidine. Deoxycytidine. Deoxyadenosine. Deoxyguanosine . Protection of the deoxyribose. Phosphorylation and phosphitylation. The coupling step. The final deprotection step. Purification methods in DNA synthesis. Characterization of oligonucleotides. Conclusion. References." @default.
- W2950577559 created "2019-06-27" @default.
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- W2950577559 date "1987-11-10" @default.
- W2950577559 modified "2023-09-26" @default.
- W2950577559 title "ChemInform Abstract: The Organic Chemistry Underlying DNA Synthesis" @default.
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- W2950577559 doi "https://doi.org/10.1002/chin.198745380" @default.
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