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• W2950579553 startingPage "535" @default.
• W2950579553 abstract "Purpose of review The spectrum of allergic eye diseases includes a variety of conditions, each characterized by complex immunopathologies. Antiallergic drugs, such as antihistamines and mast cell stabilizers, are often insufficient without concomitant topical corticosteroid treatment. The chronic course of the more severe allergic eye diseases, such as vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC), limits the treatment with topical corticosteroids to short courses. In addition, topical corticosteroid treatment puts patients at high risk of developing severe ocular complications, particularly during childhood when VKC most frequently occurs. The immunopathology of chronic diseases, such as VKC and AKC, involves predominantly T lymphocytes, and as such, immunomodulators that inhibit T-cell activation seem to be the appropriate treatment for these chronic diseases. In the past years, there is an increased incidence of managing chronic allergic eye diseases with the immunomodulator tacrolimus. The current review presents an update of the recent clinical experience with topical tacrolimus for the management of chronic allergic eye diseases. Recent findings Topical tacrolimus significantly improves the symptoms and signs of the various forms of chronic allergic eye disease. Recent studies also demonstrate the efficacy of low concentrations of topical tacrolimus for VKC. Early medical treatment with topical tacrolimus can also prevent the development of serious ocular complications of VKC, such as shield ulcers or limbal stem cell deficiency. Summary Topical tacrolimus has significantly changed the management approaches in severe and chronic allergic eye diseases and has minimized the need for topical corticosteroids." @default.
• W2950579553 created "2019-06-27" @default.
• W2950579553 creator A5015580688 @default.
• W2950579553 creator A5085994301 @default.
• W2950579553 creator A5091434667 @default.
• W2950579553 date "2019-10-01" @default.
• W2950579553 modified "2023-10-17" @default.
• W2950579553 title "Topical tacrolimus for allergic eye diseases" @default.
• W2950579553 cites W1539977736 @default.
• W2950579553 cites W1590126152 @default.
• W2950579553 cites W1972757334 @default.
• W2950579553 cites W1977059981 @default.
• W2950579553 cites W1979287119 @default.
• W2950579553 cites W1981397637 @default.
• W2950579553 cites W1984947099 @default.
• W2950579553 cites W1985107831 @default.
• W2950579553 cites W1987154640 @default.
• W2950579553 cites W1990562790 @default.
• W2950579553 cites W1990714451 @default.
• W2950579553 cites W1994482649 @default.
• W2950579553 cites W1998973585 @default.
• W2950579553 cites W1999629805 @default.
• W2950579553 cites W2005625279 @default.
• W2950579553 cites W2007370099 @default.
• W2950579553 cites W2014280584 @default.
• W2950579553 cites W2016553001 @default.
• W2950579553 cites W2021187308 @default.
• W2950579553 cites W2025573123 @default.
• W2950579553 cites W2026965073 @default.
• W2950579553 cites W2030062108 @default.
• W2950579553 cites W2030185059 @default.
• W2950579553 cites W2032219973 @default.
• W2950579553 cites W2036183227 @default.
• W2950579553 cites W2037538043 @default.
• W2950579553 cites W2038075308 @default.
• W2950579553 cites W2044086330 @default.
• W2950579553 cites W2045137114 @default.
• W2950579553 cites W2047914099 @default.
• W2950579553 cites W2048441131 @default.
• W2950579553 cites W2050205057 @default.
• W2950579553 cites W2051839108 @default.
• W2950579553 cites W2059401551 @default.
• W2950579553 cites W2066392753 @default.
• W2950579553 cites W2067545345 @default.
• W2950579553 cites W2068611987 @default.
• W2950579553 cites W2069807842 @default.
• W2950579553 cites W2070229054 @default.
• W2950579553 cites W2070431466 @default.
• W2950579553 cites W2070786707 @default.
• W2950579553 cites W2074984233 @default.
• W2950579553 cites W2078813277 @default.
• W2950579553 cites W2093269725 @default.
• W2950579553 cites W2095434140 @default.
• W2950579553 cites W2098805814 @default.
• W2950579553 cites W2099773744 @default.
• W2950579553 cites W2102551042 @default.
• W2950579553 cites W2108977819 @default.
• W2950579553 cites W2109871913 @default.
• W2950579553 cites W2117037286 @default.
• W2950579553 cites W2118025703 @default.
• W2950579553 cites W2124450032 @default.
• W2950579553 cites W2144426613 @default.
• W2950579553 cites W2145893420 @default.
• W2950579553 cites W2253179440 @default.
• W2950579553 cites W2264148261 @default.
• W2950579553 cites W2314817664 @default.
• W2950579553 cites W2329573625 @default.
• W2950579553 cites W2437337347 @default.
• W2950579553 cites W2507121048 @default.
• W2950579553 cites W2564980777 @default.
• W2950579553 cites W2604889300 @default.
• W2950579553 cites W2607427523 @default.
• W2950579553 cites W2618612036 @default.
• W2950579553 cites W2748014972 @default.
• W2950579553 cites W2761539229 @default.
• W2950579553 cites W2766453279 @default.
• W2950579553 cites W2790109950 @default.
• W2950579553 cites W2884636034 @default.
• W2950579553 cites W2891099683 @default.
• W2950579553 cites W2893152850 @default.
• W2950579553 cites W2894595464 @default.
• W2950579553 cites W2899716160 @default.
• W2950579553 cites W2906078550 @default.
• W2950579553 cites W2908706842 @default.
• W2950579553 cites W2909621737 @default.
• W2950579553 cites W2910810308 @default.
• W2950579553 cites W2911508339 @default.
• W2950579553 cites W2921322298 @default.
• W2950579553 cites W2923667890 @default.
• W2950579553 cites W2929753911 @default.
• W2950579553 cites W2946800921 @default.
• W2950579553 cites W4256186611 @default.
• W2950579553 doi "https://doi.org/10.1097/aci.0000000000000560" @default.
• W2950579553 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31169598" @default.
• W2950579553 hasPublicationYear "2019" @default.
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