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- W2950584383 abstract "A catalytic highly enantioselective Henry addition of methyl 4-nitrobutyrate to aldehydes using a Cu(II)−amino pyridine complex as catalyst is described. The products resulting from this reaction constitute a new, highly versatile family of chiral building blocks as a result of the presence of three different functional groups on the molecule. These products have been transformed into nonracemic chiral γ-lactams, 5-hydroxy-5-substituted levulinic acid derivatives, and δ-lactones." @default.
- W2950584383 created "2019-06-27" @default.
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- W2950584383 date "2010-06-10" @default.
- W2950584383 modified "2023-10-15" @default.
- W2950584383 title "Enantioselective Henry Addition of Methyl 4-Nitrobutyrate to Aldehydes. Chiral Building Blocks for 2-Pyrrolidinones and Other Derivatives" @default.
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- W2950584383 doi "https://doi.org/10.1021/ol1010888" @default.
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