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• W2950589729 abstract "The asymmetric synthesis of chiral piperazinylpropylisoxazoline analogues, (R)-(+)-1, 2 and (S)-(−)-1, 2 was accomplished through a seven-step sequence of reactions, which involved asymmetric 1,3-dipolar cycloaddition, alkyl chain extension, and reductive amination as key reactions. Chiral ligands (R)-(+)-1, 2 exhibited the higher binding affinity and selectivity for the D3 receptor over the D4 receptor than (S)-(−)-1, 2 ligands." @default.
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• W2950589729 date "2007-07-01" @default.
• W2950589729 modified "2023-10-07" @default.
• W2950589729 title "Asymmetric synthesis of chiral piperazinylpropylisoxazoline ligands for dopamine receptors" @default.
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• W2950589729 doi "https://doi.org/10.1016/j.ejmech.2006.12.030" @default.
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