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- W2950594539 abstract "A short and efficient synthesis of α-methylene-γ-butyrolactone-3-spirooxindolones by the reaction of isomerised bromo derivatives of Morita-Baylis-Hillman adducts of isatin and formaldehyde followed by acid-catalysed lactonisation has been achieved. The oxindolidino allyl bromide has been used for the first time for the allylation of aldehydes to afford a 2-oxindolidino homoallylic alcohol which on acid-catalysed lactonisation delivered the title compounds in excellent yield. Synthetic transformation of the spirolactone oxindole is demonstrated with the preparation of an oxirane derivative and a second Morita-Baylis-Hillman adduct." @default.
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- W2950594539 date "2008-10-16" @default.
- W2950594539 modified "2023-10-01" @default.
- W2950594539 title "A Short and Efficient Synthesis of 3-Spiro-α-methylene-γ-butyrolactone Oxindolones from Isomerised Bromo Derivatives of Morita-Baylis-Hillman Adducts" @default.
- W2950594539 doi "https://doi.org/10.1055/s-0028-1083549" @default.
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