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- W2950603693 abstract "Abstract A rapid and efficient, one pot synthesis of spirooxindole derivatives has been attempted by three-component reaction of isatin, malononitrile and carbonyl compound possessing a reactive α-methylene group by using task specific ionic liquid, 1-butyl-3-methyl imidazolium hydroxide [bmim]OH as a catalyst. The important features of this methodology are straight forward route in short reaction time at room temperature and avoid any hazardous organic solvent, toxic catalyst, tedious purification step. Interestingly, this protocol is not only limited to mono-systems but also to the synthesis of newer bis-spirooxindole system. The separation of the product and reusability of the catalyst are easy with excellent yield. The [bmim]OH catalyst system could be reused up to five recycles without appreciable loss of activity." @default.
- W2950603693 created "2019-06-27" @default.
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- W2950603693 date "2016-09-01" @default.
- W2950603693 modified "2023-09-23" @default.
- W2950603693 title "ChemInform Abstract: [bmim]OH: An Efficient Catalyst for the Synthesis of Mono and Bis Spirooxindole Derivatives in Ethanol at Room Temperature" @default.
- W2950603693 cites W2273360528 @default.
- W2950603693 doi "https://doi.org/10.1002/chin.201638115" @default.
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