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- W2950642275 abstract "A Lewis acid-catalyzed one-pot sequential transformation of β-keto esters, aromatic aldehydes, and NCS/NBS was reported. The reaction proceeds by way of Knoevenagel condensation/Nazarov cyclization/halogenation to give α-chloro- and α-bromo-β-keto esters in moderate yields with high diastereoselectivities. However, several aromatic aldehydes with electron-withdrawing substituents afforded unexpected α,β′-dichloro-β-keto esters in good to high yields." @default.
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- W2950642275 date "2010-04-01" @default.
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- W2950642275 title "Lewis acid-catalyzed one-pot sequential reaction for the synthesis of α-halogenated β-keto esters" @default.
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- W2950642275 doi "https://doi.org/10.1016/j.tetlet.2010.02.158" @default.
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