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- W2950689641 abstract "An efficient one-pot palladium- and copper-free procedure has been developed for a convenient synthesis of 3,5 -disubstituted-1H-pyrazoles from various acid chlorides, terminal alkynes and hydrazine by a coupling reaction and cyclocondensation sequence. Acid chlorides react with terminal alkynes in the presence of silica-supported-zinc bromide to give α,β-unsaturated ynones, and in situ conversion into pyrazoles by the hydrazine cyclocondensation." @default.
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- W2950689641 date "2015-08-01" @default.
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- W2950689641 title "Synthesis of 3,5-Disubstituted-1H-Pyrazoles from Acid Chlorides, Alkynes, and Hydrazine in the Presence of Silica-Supported-Zinc Bromide" @default.
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