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- W2950746579 abstract "Abstract The recognition of the 5′mRNA cap structure m7G(5′)ppp(5′)N by one of the components of the initiation translation machinery, the eIF4E factor, plays a pivotal role in regulation of the protein synthesis. In the present study we have shown two opposing roles of the cap phosphate chain in the specific eIF4E-cap interaction. The extension of the phosphate chain enhances the binding of the cap to the unphosphorylated eIF4E but destabilises the eIF4E-cap complex in case of the phosphorylated protein." @default.
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- W2950746579 date "2004-03-02" @default.
- W2950746579 modified "2023-10-16" @default.
- W2950746579 title "Influence of the Length of the Phosphate Chain in mRNA 5′ Cap Analogues on Their Interaction with Eukaryotic Initiation Factor 4E" @default.
- W2950746579 cites W2166834033 @default.
- W2950746579 doi "https://doi.org/10.1002/chin.200409219" @default.
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