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- W2950775788 abstract "The application of vinyloxiranes, substituted with an electron-withdrawing group, as masked dienolates in vinylogous imino-aldol reactions was achieved. Under the reaction conditions highly substituted 1,2-dihydropyridines were obtained in moderate to good yields. Mechanistic studies indicate that the reaction proceeds via the formation of an (E)-amino-α,β-unsaturated aldehyde, followed by isomerization to the (Z)-isomer, cyclization, and elimination of a water molecule, leading to the formation of the 1,2-dihydropyridine." @default.
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- W2950775788 date "2006-07-12" @default.
- W2950775788 modified "2023-10-07" @default.
- W2950775788 title "Synthesis of 1,2-Dihydropyridines Using Vinyloxiranes as Masked Dienolates in Imino-Aldol Reactions" @default.
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- W2950775788 doi "https://doi.org/10.1021/ol061086p" @default.
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