Matches in SemOpenAlex for { <https://semopenalex.org/work/W2950873799> ?p ?o ?g. }
- W2950873799 endingPage "2670" @default.
- W2950873799 startingPage "2661" @default.
- W2950873799 abstract "Abstract Cryptococcus neoformans is a pathogenic yeast capable of a unique and intriguing form of cell-to-cell transfer between macrophage cells. The mechanism for cell-to-cell transfer is not understood. In this study, we imaged mouse macrophages with CellTracker Green 5-chloromethylfluorescein diacetate–labeled cytosol to ascertain whether cytosol was shared between donor and acceptor macrophages. Analysis of several transfer events detected no transfer of cytosol from donor-to-acceptor mouse macrophages. However, blocking Fc and complement receptors resulted in a major diminution of cell-to-cell transfer events. The timing of cell-to-cell transfer (11.17 min) closely approximated the sum of phagocytosis (4.18 min) and exocytosis (6.71 min) times. We propose that macrophage cell-to-cell transfer represents a nonlytic exocytosis event, followed by phagocytosis into a macrophage that is in close proximity, and name this process Dragotcytosis (“Dragot” is a Greek surname meaning “sentinel”), as it represents sharing of a microbe between two sentinel cells of the innate immune system." @default.
- W2950873799 created "2019-06-27" @default.
- W2950873799 creator A5033281145 @default.
- W2950873799 creator A5069262789 @default.
- W2950873799 creator A5077902719 @default.
- W2950873799 date "2019-05-01" @default.
- W2950873799 modified "2023-10-11" @default.
- W2950873799 title "Dragotcytosis: Elucidation of the Mechanism for <i>Cryptococcus neoformans</i> Macrophage-to-Macrophage Transfer" @default.
- W2950873799 cites W1557813967 @default.
- W2950873799 cites W1567581543 @default.
- W2950873799 cites W1572614984 @default.
- W2950873799 cites W1967709436 @default.
- W2950873799 cites W1976681938 @default.
- W2950873799 cites W1977112775 @default.
- W2950873799 cites W1986819901 @default.
- W2950873799 cites W1999412329 @default.
- W2950873799 cites W2013686234 @default.
- W2950873799 cites W2015210137 @default.
- W2950873799 cites W2047485767 @default.
- W2950873799 cites W2056948549 @default.
- W2950873799 cites W2060197485 @default.
- W2950873799 cites W2069395166 @default.
- W2950873799 cites W2071634550 @default.
- W2950873799 cites W2080648518 @default.
- W2950873799 cites W2086181643 @default.
- W2950873799 cites W2104058719 @default.
- W2950873799 cites W2114400198 @default.
- W2950873799 cites W2118523249 @default.
- W2950873799 cites W2123303185 @default.
- W2950873799 cites W2140535415 @default.
- W2950873799 cites W2143286751 @default.
- W2950873799 cites W2154335274 @default.
- W2950873799 cites W2154604278 @default.
- W2950873799 cites W2158576875 @default.
- W2950873799 cites W2162644900 @default.
- W2950873799 cites W2164678669 @default.
- W2950873799 cites W2164961215 @default.
- W2950873799 cites W2278506590 @default.
- W2950873799 cites W2288720547 @default.
- W2950873799 cites W2487251532 @default.
- W2950873799 cites W2515870454 @default.
- W2950873799 cites W2584228215 @default.
- W2950873799 cites W2592510217 @default.
- W2950873799 cites W2807746956 @default.
- W2950873799 cites W4321835893 @default.
- W2950873799 doi "https://doi.org/10.4049/jimmunol.1801118" @default.
- W2950873799 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6495551" @default.
- W2950873799 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30877168" @default.
- W2950873799 hasPublicationYear "2019" @default.
- W2950873799 type Work @default.
- W2950873799 sameAs 2950873799 @default.
- W2950873799 citedByCount "28" @default.
- W2950873799 countsByYear W29508737992018 @default.
- W2950873799 countsByYear W29508737992019 @default.
- W2950873799 countsByYear W29508737992020 @default.
- W2950873799 countsByYear W29508737992021 @default.
- W2950873799 countsByYear W29508737992022 @default.
- W2950873799 countsByYear W29508737992023 @default.
- W2950873799 crossrefType "journal-article" @default.
- W2950873799 hasAuthorship W2950873799A5033281145 @default.
- W2950873799 hasAuthorship W2950873799A5069262789 @default.
- W2950873799 hasAuthorship W2950873799A5077902719 @default.
- W2950873799 hasBestOaLocation W29508737991 @default.
- W2950873799 hasConcept C1491633281 @default.
- W2950873799 hasConcept C160448771 @default.
- W2950873799 hasConcept C175969161 @default.
- W2950873799 hasConcept C181199279 @default.
- W2950873799 hasConcept C202751555 @default.
- W2950873799 hasConcept C2777893358 @default.
- W2950873799 hasConcept C2779244956 @default.
- W2950873799 hasConcept C49039625 @default.
- W2950873799 hasConcept C55493867 @default.
- W2950873799 hasConcept C86803240 @default.
- W2950873799 hasConcept C89423630 @default.
- W2950873799 hasConcept C95444343 @default.
- W2950873799 hasConcept C98539663 @default.
- W2950873799 hasConceptScore W2950873799C1491633281 @default.
- W2950873799 hasConceptScore W2950873799C160448771 @default.
- W2950873799 hasConceptScore W2950873799C175969161 @default.
- W2950873799 hasConceptScore W2950873799C181199279 @default.
- W2950873799 hasConceptScore W2950873799C202751555 @default.
- W2950873799 hasConceptScore W2950873799C2777893358 @default.
- W2950873799 hasConceptScore W2950873799C2779244956 @default.
- W2950873799 hasConceptScore W2950873799C49039625 @default.
- W2950873799 hasConceptScore W2950873799C55493867 @default.
- W2950873799 hasConceptScore W2950873799C86803240 @default.
- W2950873799 hasConceptScore W2950873799C89423630 @default.
- W2950873799 hasConceptScore W2950873799C95444343 @default.
- W2950873799 hasConceptScore W2950873799C98539663 @default.
- W2950873799 hasIssue "9" @default.
- W2950873799 hasLocation W29508737991 @default.
- W2950873799 hasLocation W29508737992 @default.
- W2950873799 hasLocation W29508737993 @default.
- W2950873799 hasLocation W29508737994 @default.
- W2950873799 hasLocation W29508737995 @default.
- W2950873799 hasOpenAccess W2950873799 @default.
- W2950873799 hasPrimaryLocation W29508737991 @default.
- W2950873799 hasRelatedWork W1942549621 @default.