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- W2950876768 abstract "ABSTRACT One of many important features of the tumour microenvironment is that it is a place of active Darwinian selection where different tumour clones become adapted to the variety of ecological niches that make up the microenvironment. These evolutionary processes turn the microenvironment into a powerful source of tumour heterogeneity and contribute to the development of drug resistance in cancer. Here, we describe a computational tool to study the ecology of the microenvironment and report results about the ecology of the tumour microenvironment and its evolutionary dynamics." @default.
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- W2950876768 date "2019-06-06" @default.
- W2950876768 modified "2023-09-26" @default.
- W2950876768 title "Fine-grained simulations of the microenvironment of vascularized tumours" @default.
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- W2950876768 doi "https://doi.org/10.1101/661603" @default.
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