FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2950892749> ?p ?o ?g. }

• W2950892749 abstract "ABSTRACT The advent of the genomic era has made elucidating gene function at large scale a pressing challenge. ORFeome collections, whereby almost all ORFs of a given species are cloned and can be subsequently leveraged in multiple functional genomic approaches, represent valuable resources towards this endeavor. Here we provide novel, genome-scale tools for the study of Candida albicans , a commensal yeast that is also responsible for frequent superficial and disseminated infections in humans. We have generated an ORFeome collection composed of 5,102 ORFs cloned in a Gateway ™ donor vector, representing 83% of the currently annotated coding sequences of C. albicans . Sequencing data of the cloned ORFs are available in the CandidaOrfDB database at http://candidaorfeome.eu . We also engineered 49 expression vectors with a choice of promoters, tags, and selection markers and demonstrated their applicability to the study of target ORFs transferred from the C. albicans ORFeome. In addition, the use of the ORFeome in the detection of protein-protein interaction was demonstrated. Mating-compatible strains as well as Gateway ™ -compatible two-hybrid vectors were engineered, validated and used in a proof of concept experiment. These unique and valuable resources should greatly facilitate future functional studies in C. albicans and the elucidation of mechanisms that underlie its pathogenicity." @default.
• W2950892749 created "2019-06-27" @default.
• W2950892749 creator A5004731635 @default.
• W2950892749 creator A5006954173 @default.
• W2950892749 creator A5022953102 @default.
• W2950892749 creator A5030114899 @default.
• W2950892749 creator A5030708482 @default.
• W2950892749 creator A5033199827 @default.
• W2950892749 creator A5036164570 @default.
• W2950892749 creator A5044808709 @default.
• W2950892749 creator A5047118089 @default.
• W2950892749 creator A5052971639 @default.
• W2950892749 creator A5053225241 @default.
• W2950892749 creator A5054682428 @default.
• W2950892749 creator A5061177533 @default.
• W2950892749 creator A5061870391 @default.
• W2950892749 creator A5064167107 @default.
• W2950892749 creator A5065427838 @default.
• W2950892749 creator A5070205842 @default.
• W2950892749 creator A5072855877 @default.
• W2950892749 creator A5075596656 @default.
• W2950892749 creator A5078857725 @default.
• W2950892749 creator A5078951007 @default.
• W2950892749 creator A5086618179 @default.
• W2950892749 creator A5087058935 @default.
• W2950892749 creator A5088449484 @default.
• W2950892749 creator A5089235014 @default.
• W2950892749 creator A5090068893 @default.
• W2950892749 date "2018-02-08" @default.
• W2950892749 modified "2023-10-01" @default.
• W2950892749 title "Generating genomic platforms to study<i>Candida albicans</i>pathogenesis" @default.
• W2950892749 cites W1503938960 @default.
• W2950892749 cites W1563231805 @default.
• W2950892749 cites W1761291524 @default.
• W2950892749 cites W1894827346 @default.
• W2950892749 cites W1968574388 @default.
• W2950892749 cites W1969395447 @default.
• W2950892749 cites W1976281822 @default.
• W2950892749 cites W1985484513 @default.
• W2950892749 cites W1990474165 @default.
• W2950892749 cites W2013947447 @default.
• W2950892749 cites W2020042020 @default.
• W2950892749 cites W2025947534 @default.
• W2950892749 cites W2026969336 @default.
• W2950892749 cites W2041607735 @default.
• W2950892749 cites W2041611856 @default.
• W2950892749 cites W2042161296 @default.
• W2950892749 cites W2049219353 @default.
• W2950892749 cites W2049505636 @default.
• W2950892749 cites W2050861916 @default.
• W2950892749 cites W2051122649 @default.
• W2950892749 cites W2064795801 @default.
• W2950892749 cites W2066665409 @default.
• W2950892749 cites W2068826765 @default.
• W2950892749 cites W2070988196 @default.
• W2950892749 cites W2073082596 @default.
• W2950892749 cites W2077686032 @default.
• W2950892749 cites W2085762947 @default.
• W2950892749 cites W2092296116 @default.
• W2950892749 cites W2094285560 @default.
• W2950892749 cites W2102276726 @default.
• W2950892749 cites W2102429461 @default.
• W2950892749 cites W2107228478 @default.
• W2950892749 cites W2115943422 @default.
• W2950892749 cites W2120191560 @default.
• W2950892749 cites W2120365200 @default.
• W2950892749 cites W2128207311 @default.
• W2950892749 cites W2132417094 @default.
• W2950892749 cites W2137775778 @default.
• W2950892749 cites W2139307267 @default.
• W2950892749 cites W2140518858 @default.
• W2950892749 cites W2140935709 @default.
• W2950892749 cites W2143564701 @default.
• W2950892749 cites W2145518850 @default.
• W2950892749 cites W2145804339 @default.
• W2950892749 cites W2151111689 @default.
• W2950892749 cites W2151326362 @default.
• W2950892749 cites W2152987385 @default.
• W2950892749 cites W2155758168 @default.
• W2950892749 cites W2158227899 @default.
• W2950892749 cites W2161206249 @default.
• W2950892749 cites W2162117109 @default.
• W2950892749 cites W2167460646 @default.
• W2950892749 cites W2169788158 @default.
• W2950892749 cites W2171591233 @default.
• W2950892749 cites W2404060170 @default.
• W2950892749 cites W2410178177 @default.
• W2950892749 cites W2530772399 @default.
• W2950892749 cites W8380531 @default.
• W2950892749 cites W986136330 @default.
• W2950892749 doi "https://doi.org/10.1101/261628" @default.
• W2950892749 hasPublicationYear "2018" @default.
• W2950892749 type Work @default.
• W2950892749 sameAs 2950892749 @default.
• W2950892749 citedByCount "0" @default.
• W2950892749 crossrefType "posted-content" @default.
• W2950892749 hasAuthorship W2950892749A5004731635 @default.
• W2950892749 hasAuthorship W2950892749A5006954173 @default.
• W2950892749 hasAuthorship W2950892749A5022953102 @default.
• W2950892749 hasAuthorship W2950892749A5030114899 @default.

• next