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• W2950963875 abstract "Abstract Plant-pathogenic fungi secrete effector proteins to facilitate infection. We describe extensive improvements to EffectorP, the first machine learning classifier for fungal effector prediction. EffectorP 2.0 is now trained on a larger set of effectors and utilizes a different approach based on an ensemble of classifiers trained on different subsets of negative data, offering different views on classification. EffectorP 2.0 achieves accuracy of 89%, compared to 82% for EffectorP 1.0 and 59.8% for a small size classifier. Important features for effector prediction appear to be protein size, protein net charge as well as the amino acids serine and cysteine. EffectorP 2.0 decreases the number of predicted effectors in secretomes of fungal plant symbionts and saprophytes by 40% when compared to EffectorP 1.0. However, EffectorP 1.0 retains value and combining EffectorP 1.0 and 2.0 results in a stringent classifier with low false positive rate of 9%. EffectorP 2.0 predicts significant enrichments of effectors in 12 out of 13 sets of infection-induced proteins from diverse fungal pathogens, whereas a small cysteine-rich classifier detects enrichment only in 7 out of 13. EffectorP 2.0 will fast-track prioritization of high-confidence effector candidates for functional validation and aid in improving our understanding of effector biology. EffectorP 2.0 is available at http://effectorp.csiro.au ." @default.
• W2950963875 created "2019-06-27" @default.
• W2950963875 creator A5014680668 @default.
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• W2950963875 creator A5077228817 @default.
• W2950963875 creator A5077802253 @default.
• W2950963875 date "2018-01-19" @default.
• W2950963875 modified "2023-10-14" @default.
• W2950963875 title "Improved prediction of fungal effector proteins from secretomes with EffectorP 2.0" @default.
• W2950963875 cites W1965961606 @default.
• W2950963875 cites W1970871100 @default.
• W2950963875 cites W1974116356 @default.
• W2950963875 cites W1975078409 @default.
• W2950963875 cites W1979613935 @default.
• W2950963875 cites W1979692920 @default.
• W2950963875 cites W1988368360 @default.
• W2950963875 cites W1991993713 @default.
• W2950963875 cites W1996423252 @default.
• W2950963875 cites W1998671658 @default.
• W2950963875 cites W2000991379 @default.
• W2950963875 cites W2001402566 @default.
• W2950963875 cites W2003266704 @default.
• W2950963875 cites W2007497503 @default.
• W2950963875 cites W2009815491 @default.
• W2950963875 cites W2020994501 @default.
• W2950963875 cites W2022414939 @default.
• W2950963875 cites W2033174994 @default.
• W2950963875 cites W2039514696 @default.
• W2950963875 cites W2039853174 @default.
• W2950963875 cites W2041825338 @default.
• W2950963875 cites W2042206503 @default.
• W2950963875 cites W2049505636 @default.
• W2950963875 cites W2051731650 @default.
• W2950963875 cites W2061803253 @default.
• W2950963875 cites W2065695795 @default.
• W2950963875 cites W2082120419 @default.
• W2950963875 cites W2088989333 @default.
• W2950963875 cites W2094070028 @default.
• W2950963875 cites W2094201044 @default.
• W2950963875 cites W2095699986 @default.
• W2950963875 cites W2098669490 @default.
• W2950963875 cites W2099117928 @default.
• W2950963875 cites W2105106957 @default.
• W2950963875 cites W2107276925 @default.
• W2950963875 cites W2110040181 @default.
• W2950963875 cites W2114835024 @default.
• W2950963875 cites W2120938541 @default.
• W2950963875 cites W2126763121 @default.
• W2950963875 cites W2128606612 @default.
• W2950963875 cites W2131496416 @default.
• W2950963875 cites W2133990480 @default.
• W2950963875 cites W2134233898 @default.
• W2950963875 cites W2135621733 @default.
• W2950963875 cites W2136089916 @default.
• W2950963875 cites W2140602911 @default.
• W2950963875 cites W2145608020 @default.
• W2950963875 cites W2151177060 @default.
• W2950963875 cites W2152458080 @default.
• W2950963875 cites W2152770371 @default.
• W2950963875 cites W2153283265 @default.
• W2950963875 cites W2155078412 @default.
• W2950963875 cites W2157380302 @default.
• W2950963875 cites W2158195770 @default.
• W2950963875 cites W2161479301 @default.
• W2950963875 cites W2161746138 @default.
• W2950963875 cites W2162002946 @default.
• W2950963875 cites W2162759662 @default.
• W2950963875 cites W2165758921 @default.
• W2950963875 cites W2165759219 @default.
• W2950963875 cites W2165876708 @default.
• W2950963875 cites W2167493116 @default.
• W2950963875 cites W2171209136 @default.
• W2950963875 cites W2171468101 @default.
• W2950963875 cites W2173883987 @default.
• W2950963875 cites W2213426519 @default.
• W2950963875 cites W2278344208 @default.
• W2950963875 cites W2473499314 @default.
• W2950963875 cites W2476847756 @default.
• W2950963875 cites W2529301660 @default.
• W2950963875 cites W2550585340 @default.
• W2950963875 cites W2557145672 @default.
• W2950963875 cites W2560844000 @default.
• W2950963875 cites W2613053348 @default.
• W2950963875 cites W2765671382 @default.
• W2950963875 cites W2775877430 @default.
• W2950963875 cites W2776178524 @default.
• W2950963875 cites W2949819099 @default.
• W2950963875 cites W2949972760 @default.
• W2950963875 cites W374729652 @default.
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• W2950963875 doi "https://doi.org/10.1101/250464" @default.
• W2950963875 hasPublicationYear "2018" @default.
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