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- W2951053677 abstract "An organocatalyst-mediated, asymmetric Mannich reaction in the presence of water without using organic solvents has been developed. A highly reactive siloxytetrazole hybrid catalyst has been developed for the reaction of dimethoxyacetaldehyde, while the sodium salt of siloxyproline is an effective catalyst of α-imino glyoxylate. Excellent enantioselectivity can be realized, and the usage of organic solvents can be reduced compared to the conventional reactions in organic solvents." @default.
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- W2951053677 date "2007-12-04" @default.
- W2951053677 modified "2023-10-16" @default.
- W2951053677 title "Organic Solvent-Free, Enantio- and Diastereoselective, Direct Mannich Reaction in the Presence of Water" @default.
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- W2951053677 doi "https://doi.org/10.1021/ol702489k" @default.
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