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- W2951119073 abstract "The incidence of acute kidney injury (AKI) after cardiac surgery appears to have increased, 1 Neugarten J Sandilya S Singh B Golestaneh L Sex and the risk of AKI following cardio-thoracic surgery: a meta-analysis. Clin J Am Soc Nephrol. 2016; 11: 2113-2122 Crossref PubMed Scopus (37) Google Scholar especially among older patients with increasing comorbidities. 2 Nadim MK Forni LG Bihorac A et al. Cardiac and vascular surgery-associated acute kidney injury: the 20th International Consensus Conference of the ADQI (Acute Disease Quality Initiative) Group. J Am Heart Assoc. 2018; 7: e008834 Crossref PubMed Scopus (93) Google Scholar Although some patients who undergo cardiac surgery develop mild AKI and recover apparently well, others have catastrophic AKI requiring renal replacement therapy. Not uncommonly, patients follow a protracted clinical course beyond the usual 7-day timespan and maintain renal dysfunction for up to 90 days (acute kidney disease) or it evolves into chronic kidney disease (CKD) or end-stage kidney failure. 3 See EJ Jayasinghe K Glassford N et al. Long-term risk of adverse outcomes after acute kidney injury: a systematic review and meta-analysis of cohort studies using consensus definitions of exposure. Kidney Int. 2019; 95: 160-172 Summary Full Text Full Text PDF PubMed Scopus (151) Google Scholar Association between urinary dickkopf-3, acute kidney injury, and subsequent loss of kidney function in patients undergoing cardiac surgery: an observational cohort studyPreoperative urinary DKK3 is an independent predictor for postoperative AKI and for subsequent loss of kidney function. Urinary DKK3 might aid in the identification of patients in whom preventive treatment strategies are effective. Full-Text PDF" @default.
- W2951119073 created "2019-06-27" @default.
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- W2951119073 date "2019-08-01" @default.
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- W2951119073 title "A biomarker able to predict acute kidney injury before it occurs?" @default.
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- W2951119073 doi "https://doi.org/10.1016/s0140-6736(19)30843-8" @default.
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