FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2951153492> ?p ?o ?g. }

• W2951153492 abstract "Spiral cleavage is a conserved, early developmental mode found in several phyla of Lophotrochozoans resulting in highly diverse adult body plans. While the cleavage pattern has clearly been broadly conserved, it has also undergone many modifications in various taxa. The precise mechanisms of how different adaptations have altered the ancestral spiral cleavage pattern are an important ongoing evolutionary question, and adequately answering this question requires obtaining a broad developmental knowledge of different spirally cleaving taxa. In flatworms (Platyhelminthes), the spiral cleavage program has been lost or severely modified in most taxa. Polyclad flatworms, however, have retained the pattern up to the 32-cell stage. Here we study early embryogenesis of the cotylean polyclad flatworm Maritigrella crozieri to investigate how closely this species follows the canonical spiral cleavage pattern and to discover any potential deviations from it. Using live imaging recordings and 3D reconstructions of embryos, we give a detailed picture of the events that occur during spiral cleavage in M. crozieri. We suggest, contrary to previous observations, that the four-cell stage is a product of unequal cleavages. We show that that the formation of third and fourth micromere quartets is accompanied by strong blebbing events; blebbing also accompanies the formation of micromere 4d. We find an important deviation from the canonical pattern of cleavages with clear evidence that micromere 4d follows an atypical cleavage pattern, so far exclusively found in polyclad flatworms. Our findings highlight that early development in M. crozieri deviates in several important aspects from the canonical spiral cleavage pattern. We suggest that some of our observations extend to polyclad flatworms in general as they have been described in both suborders of the Polycladida, the Cotylea and Acotylea." @default.
• W2951153492 created "2019-06-27" @default.
• W2951153492 creator A5023865550 @default.
• W2951153492 creator A5074431478 @default.
• W2951153492 date "2019-06-22" @default.
• W2951153492 modified "2023-10-13" @default.
• W2951153492 title "Reinvestigating the early embryogenesis in the flatworm Maritigrella crozieri highlights the unique spiral cleavage program found in polyclad flatworms" @default.
• W2951153492 cites W151401630 @default.
• W2951153492 cites W1687439539 @default.
• W2951153492 cites W1905981005 @default.
• W2951153492 cites W1964830143 @default.
• W2951153492 cites W1965776353 @default.
• W2951153492 cites W1967254083 @default.
• W2951153492 cites W1967754711 @default.
• W2951153492 cites W1969343423 @default.
• W2951153492 cites W1972708386 @default.
• W2951153492 cites W1972864527 @default.
• W2951153492 cites W1976430186 @default.
• W2951153492 cites W1979676973 @default.
• W2951153492 cites W1981075496 @default.
• W2951153492 cites W1985806763 @default.
• W2951153492 cites W1990174928 @default.
• W2951153492 cites W1995431275 @default.
• W2951153492 cites W2000108466 @default.
• W2951153492 cites W2003844978 @default.
• W2951153492 cites W2006019567 @default.
• W2951153492 cites W2006635809 @default.
• W2951153492 cites W2011124999 @default.
• W2951153492 cites W2015458166 @default.
• W2951153492 cites W2018891055 @default.
• W2951153492 cites W2021100834 @default.
• W2951153492 cites W2023170849 @default.
• W2951153492 cites W2024331608 @default.
• W2951153492 cites W2029404034 @default.
• W2951153492 cites W2029482176 @default.
• W2951153492 cites W2033227337 @default.
• W2951153492 cites W2037364167 @default.
• W2951153492 cites W2039772754 @default.
• W2951153492 cites W2047748032 @default.
• W2951153492 cites W2048039415 @default.
• W2951153492 cites W2049784603 @default.
• W2951153492 cites W2052872982 @default.
• W2951153492 cites W2056942342 @default.
• W2951153492 cites W2067144256 @default.
• W2951153492 cites W2068223477 @default.
• W2951153492 cites W2068743686 @default.
• W2951153492 cites W2069840520 @default.
• W2951153492 cites W2073857918 @default.
• W2951153492 cites W2074966513 @default.
• W2951153492 cites W2076514478 @default.
• W2951153492 cites W2081699669 @default.
• W2951153492 cites W2085445084 @default.
• W2951153492 cites W2092363739 @default.
• W2951153492 cites W2093490284 @default.
• W2951153492 cites W2095801320 @default.
• W2951153492 cites W2096641211 @default.
• W2951153492 cites W2097382641 @default.
• W2951153492 cites W2097863014 @default.
• W2951153492 cites W2106675234 @default.
• W2951153492 cites W2111554513 @default.
• W2951153492 cites W2116847269 @default.
• W2951153492 cites W2136585859 @default.
• W2951153492 cites W2144229323 @default.
• W2951153492 cites W2147126800 @default.
• W2951153492 cites W2150097277 @default.
• W2951153492 cites W2152796769 @default.
• W2951153492 cites W2161533644 @default.
• W2951153492 cites W2162611989 @default.
• W2951153492 cites W2167279371 @default.
• W2951153492 cites W2167803613 @default.
• W2951153492 cites W2188052837 @default.
• W2951153492 cites W2244649948 @default.
• W2951153492 cites W2463778280 @default.
• W2951153492 cites W2529393477 @default.
• W2951153492 cites W2773935784 @default.
• W2951153492 cites W2908647854 @default.
• W2951153492 cites W3091219223 @default.
• W2951153492 doi "https://doi.org/10.1186/s13227-019-0126-5" @default.
• W2951153492 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6588950" @default.
• W2951153492 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31285819" @default.
• W2951153492 hasPublicationYear "2019" @default.
• W2951153492 type Work @default.
• W2951153492 sameAs 2951153492 @default.
• W2951153492 citedByCount "7" @default.
• W2951153492 countsByYear W29511534922020 @default.
• W2951153492 countsByYear W29511534922022 @default.
• W2951153492 countsByYear W29511534922023 @default.
• W2951153492 crossrefType "journal-article" @default.
• W2951153492 hasAuthorship W2951153492A5023865550 @default.
• W2951153492 hasAuthorship W2951153492A5074431478 @default.
• W2951153492 hasBestOaLocation W29511534921 @default.
• W2951153492 hasConcept C151730666 @default.
• W2951153492 hasConcept C175156509 @default.
• W2951153492 hasConcept C183074962 @default.
• W2951153492 hasConcept C2781355164 @default.
• W2951153492 hasConcept C43369102 @default.
• W2951153492 hasConcept C71640776 @default.
• W2951153492 hasConcept C78458016 @default.
• W2951153492 hasConcept C86803240 @default.
• W2951153492 hasConcept C90856448 @default.

• next