Matches in SemOpenAlex for { <https://semopenalex.org/work/W2951180778> ?p ?o ?g. }
- W2951180778 abstract "Citramalate is an attractive biotechnology target because it is a precursor of methylmethacrylate, which is used to manufacture Perspex and other high-value products. Engineered E. coli strains are able to produce high titers of citramalate, despite having to express a foreign enzyme and tolerate the presence of a nonnative biochemical. A systems analysis of the citramalate fermentation was undertaken to uncover the reasons underpinning its productivity. This showed that E. coli readily adjusts to the redirection of metabolic resources toward recombinant protein and citramalate production and suggests that E. coli is an excellent chassis for manufacturing similar small, polar, foreign molecules." @default.
- W2951180778 created "2019-06-27" @default.
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- W2951180778 date "2019-08-27" @default.
- W2951180778 modified "2023-10-18" @default.
- W2951180778 title "Systems Analyses Reveal the Resilience of Escherichia coli Physiology during Accumulation and Export of the Nonnative Organic Acid Citramalate" @default.
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- W2951180778 doi "https://doi.org/10.1128/msystems.00187-19" @default.
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