FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2951301420> ?p ?o ?g. }

• W2951301420 endingPage "2100" @default.
• W2951301420 startingPage "2093" @default.
• W2951301420 abstract "Background and Purpose— Bridging therapy with low-molecular-weight heparin reportedly leads to a worse outcome for acute cardioembolic stroke patients because of a higher incidence of intracerebral bleeding. However, this practice is common in clinical settings. This observational study aimed to compare (1) the clinical profiles of patients receiving and not receiving bridging therapy, (2) overall group outcomes, and (3) outcomes according to the type of anticoagulant prescribed. Methods— We analyzed data of patients from the prospective RAF and RAF-NOACs studies. The primary outcome was defined as the composite of ischemic stroke, transient ischemic attack, systemic embolism, symptomatic cerebral bleeding, and major extracerebral bleeding observed at 90 days after the acute stroke. Results— Of 1810 patients who initiated oral anticoagulant therapy, 371 (20%) underwent bridging therapy with full-dose low-molecular-weight heparin. Older age and the presence of leukoaraiosis were inversely correlated with the use of bridging therapy. Forty-two bridged patients (11.3%) reached the combined outcome versus 72 (5.0%) of the nonbridged patients ( P =0.0001). At multivariable analysis, bridging therapy was associated with the composite end point (odds ratio, 2.3; 95% CI, 1.4–3.7; P <0.0001), as well as ischemic (odds ratio, 2.2; 95% CI, 1.3–3.9; P =0.005) and hemorrhagic (odds ratio, 2.4; 95% CI, 1.2–4.9; P =0.01) end points separately. Conclusions— Our findings suggest that patients receiving low-molecular-weight heparin have a higher risk of early ischemic recurrence and hemorrhagic transformation compared with nonbridged patients." @default.
• W2951301420 created "2019-06-27" @default.
• W2951301420 creator A5000034377 @default.
• W2951301420 creator A5000056014 @default.
• W2951301420 creator A5000302445 @default.
• W2951301420 creator A5000427468 @default.
• W2951301420 creator A5003393259 @default.
• W2951301420 creator A5003504773 @default.
• W2951301420 creator A5003622109 @default.
• W2951301420 creator A5003961762 @default.
• W2951301420 creator A5004350212 @default.
• W2951301420 creator A5004980235 @default.
• W2951301420 creator A5006813553 @default.
• W2951301420 creator A5007109847 @default.
• W2951301420 creator A5008224042 @default.
• W2951301420 creator A5009025017 @default.
• W2951301420 creator A5009067298 @default.
• W2951301420 creator A5010662353 @default.
• W2951301420 creator A5011978656 @default.
• W2951301420 creator A5013802927 @default.
• W2951301420 creator A5016574218 @default.
• W2951301420 creator A5018610569 @default.
• W2951301420 creator A5020590501 @default.
• W2951301420 creator A5020815283 @default.
• W2951301420 creator A5021210152 @default.
• W2951301420 creator A5021457180 @default.
• W2951301420 creator A5021615854 @default.
• W2951301420 creator A5022075992 @default.
• W2951301420 creator A5022472213 @default.
• W2951301420 creator A5022557432 @default.
• W2951301420 creator A5022665738 @default.
• W2951301420 creator A5022727289 @default.
• W2951301420 creator A5023212844 @default.
• W2951301420 creator A5023490483 @default.
• W2951301420 creator A5024359683 @default.
• W2951301420 creator A5025237260 @default.
• W2951301420 creator A5028464878 @default.
• W2951301420 creator A5029230162 @default.
• W2951301420 creator A5029686342 @default.
• W2951301420 creator A5032594788 @default.
• W2951301420 creator A5032865224 @default.
• W2951301420 creator A5033206744 @default.
• W2951301420 creator A5033356415 @default.
• W2951301420 creator A5033735435 @default.
• W2951301420 creator A5035115996 @default.
• W2951301420 creator A5035404137 @default.
• W2951301420 creator A5036215544 @default.
• W2951301420 creator A5039005212 @default.
• W2951301420 creator A5039618335 @default.
• W2951301420 creator A5040344593 @default.
• W2951301420 creator A5042993713 @default.
• W2951301420 creator A5043754825 @default.
• W2951301420 creator A5043756231 @default.
• W2951301420 creator A5046622037 @default.
• W2951301420 creator A5046704804 @default.
• W2951301420 creator A5050030337 @default.
• W2951301420 creator A5050506462 @default.
• W2951301420 creator A5051285441 @default.
• W2951301420 creator A5051879610 @default.
• W2951301420 creator A5052696387 @default.
• W2951301420 creator A5052702757 @default.
• W2951301420 creator A5052877203 @default.
• W2951301420 creator A5053682062 @default.
• W2951301420 creator A5054783539 @default.
• W2951301420 creator A5055048928 @default.
• W2951301420 creator A5055292769 @default.
• W2951301420 creator A5058622059 @default.
• W2951301420 creator A5060076631 @default.
• W2951301420 creator A5061445522 @default.
• W2951301420 creator A5064108429 @default.
• W2951301420 creator A5065952002 @default.
• W2951301420 creator A5066090364 @default.
• W2951301420 creator A5067678081 @default.
• W2951301420 creator A5068131006 @default.
• W2951301420 creator A5069697936 @default.
• W2951301420 creator A5069932981 @default.
• W2951301420 creator A5070954507 @default.
• W2951301420 creator A5075801309 @default.
• W2951301420 creator A5076026606 @default.
• W2951301420 creator A5077453387 @default.
• W2951301420 creator A5077537095 @default.
• W2951301420 creator A5079574532 @default.
• W2951301420 creator A5079774183 @default.
• W2951301420 creator A5081041579 @default.
• W2951301420 creator A5081253992 @default.
• W2951301420 creator A5081836436 @default.
• W2951301420 creator A5082165646 @default.
• W2951301420 creator A5082697637 @default.
• W2951301420 creator A5082948301 @default.
• W2951301420 creator A5085014420 @default.
• W2951301420 creator A5085144463 @default.
• W2951301420 creator A5086298713 @default.
• W2951301420 creator A5086314824 @default.
• W2951301420 creator A5086641146 @default.
• W2951301420 creator A5087139584 @default.
• W2951301420 creator A5088364999 @default.
• W2951301420 creator A5088674770 @default.
• W2951301420 creator A5088791721 @default.

• next