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- W2951339491 abstract "An expeditious and practical method for the reduction of amides to amines is reported. The method consists of activation of amides with TMSCl followed by reduction with LiAlH4. Various amides/lactams including hindered amides and secondary amides gave the corresponding amines in good to excellent yields. This novel protocol has a wide substrate scope and shows good functional group tolerance with high stereoretention." @default.
- W2951339491 created "2019-06-27" @default.
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- W2951339491 date "2013-09-01" @default.
- W2951339491 modified "2023-09-24" @default.
- W2951339491 title "Amide activation by TMSCl: reduction of amides to amines by LiAlH4 under mild conditions" @default.
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- W2951339491 doi "https://doi.org/10.1016/j.tetlet.2013.06.144" @default.
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