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- W2951359398 abstract "Mycobacterium tuberculosis remains a widespread and devastating human pathogen. Presented here is the characterization of an atypical class I diterpene cyclase from M. tuberculosis that catalyzes an unusual cyclization reaction in converting the known M. tuberculosis metabolite halimadienyl diphosphate to a further cyclized novel diterpene, which we have termed edaxadiene, as it directly inhibits maturation of the phagosomal compartment in which the bacterium is taken up during infection." @default.
- W2951359398 created "2019-06-27" @default.
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- W2951359398 date "2010-04-20" @default.
- W2951359398 modified "2023-09-27" @default.
- W2951359398 title "ChemInform Abstract: Edaxadiene: A New Bioactive Diterpene from Mycobacterium tuberculosis." @default.
- W2951359398 cites W2074383803 @default.
- W2951359398 doi "https://doi.org/10.1002/chin.201016180" @default.
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