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- W2951382015 abstract "Abstract 3,6,9-Trioxaundecane-1,11-diisocyanate (6) was synthesised from tetraethylene glycol in 5 steps and 48 % overall yield. Spacer 6 was monofunctionalised with the fully protected adenosyl-3′-O-succinate derivative 7 and linked to aminomethyl polystyrene affording a solid support suitable for oligoribonucleotide synthesis (loading: ∼20 μmol/g). The HPLC analysis of a crude oligoribonucleotide synthesis and the yield of the full-length product show that this spacer compares well to hexamethylene diamine." @default.
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- W2951382015 date "2010-06-19" @default.
- W2951382015 modified "2023-09-24" @default.
- W2951382015 title "ChemInform Abstract: Tetraethylene Glycol-Derived Spacer for Oligonucleotide Synthesis." @default.
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- W2951382015 doi "https://doi.org/10.1002/chin.199845249" @default.
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