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- W2951427690 abstract "Methods for the cyclodehydration of N-(aminoalkyl)benzamides are few and employ harsh reaction conditions. We have found that the easily prepared phosphonium anhydrides 1 (Hendrickson reagent) or 2 can be used for cyclodehydration of N-(aminoalkyl)benzamides under very mild conditions (room temperature) to produce five-, six-, and seven-membered cyclic amidines. Good yields are obtained by employing a temporary trityl group protection strategy. Cyclic analogue 2 can be used when the product cyclic amidine is organic-soluble, thus producing water-soluble byproducts." @default.
- W2951427690 created "2019-06-27" @default.
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- W2951427690 date "2013-11-08" @default.
- W2951427690 modified "2023-09-23" @default.
- W2951427690 title "ChemInform Abstract: Cyclodehydration of N-(Aminoalkyl)benzamides under Mild Conditions with a Hendrickson Reagent Analogue." @default.
- W2951427690 cites W2009508268 @default.
- W2951427690 doi "https://doi.org/10.1002/chin.201348039" @default.
- W2951427690 hasPublicationYear "2013" @default.
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