FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2951453112> ?p ?o ?g. }

• W2951453112 endingPage "775" @default.
• W2951453112 startingPage "775" @default.
• W2951453112 abstract "Background: During the induction phase of the treatment exist several factors, besides glycemia control, that predisposed to severe infections like decreased immunity, aplasia of the epithelia, disease activity and chemotoxicity.13 But the effect of hyperglycemia during induction to remission have impact the leukemia-free survival (LFS) results. Aims: The purpose of this study is to determine the incidence of hyperglycemia in therapeutic programs that include dexamethasone during the induction, and compare leukemia free survival (LFS) and disease-free survival (DFS) in patients older than 15 years Methods: We performed a unicentric, longitudinal, case control study in ALL patients older than 15 years old admitted to the adult hematology Service of the CMN “20 de Noviembre” during the period from 2000 to 2014 treatment with the chemotherapy. Exclusion criteria: history of myelodysplastic syndrome, previous chemotherapy and / or radiotherapy, HIV infection or any condition that precluded their inclusion in chemotherapy (CT) protocols. Patients who abandoned the treatment, who violated the chemotherapy protocol or went to BMT due to high risk disease, were eliminated. Both therapeutic programs (LAL-6 and LAL-10) included 4 days of IV dexamethasone (pre-induction phase) before the start of CT. Results: We included 159 patients, 77 women and 82 men; 77 patients presented hyperglycemia during induction phase. The mean follow-up was 19 months (2 to 61). Hyperglycemia incidence was 51.5%. The LAL-6 protocol was received by 56 patients (53% of the group without hyperglycemia and 17% in the hyperglycemia group). The LAL-10 protocol was used in 102 patients (47% and 83% respectably). The highest elevations occur immediately after concluding the use of dexamethasone, with hyperglycemia in 91 patients and without in 68. This phenomenon maintained until the end of induction and the levels of glucose start to decrease in the following phases (p = 0.0001). In patients with hyperglycemia at the end of the induction, the average age was 44 years (SD 13) and in those who did not have it was 31 years (SD 12), p = 0. 0001. Summary/Conclusion: In the multivariate analysis, the factors that predict the appearance of hyperglycemia, in our experience, were age, female sex, the existence of diabetes and the basal glucose level (> 135 mg / dL). O" @default.
• W2951453112 created "2019-06-27" @default.
• W2951453112 creator A5019994404 @default.
• W2951453112 creator A5044384633 @default.
• W2951453112 creator A5061048634 @default.
• W2951453112 creator A5064564382 @default.
• W2951453112 creator A5069814716 @default.
• W2951453112 creator A5081488322 @default.
• W2951453112 creator A5088239923 @default.
• W2951453112 creator A5091049255 @default.
• W2951453112 date "2019-06-01" @default.
• W2951453112 modified "2023-09-26" @default.
• W2951453112 title "PB1680 SURVIVAL OF ADULT PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA (PH NEG) WHO DEVELOP HYPERGLYCEMIA DURING THE INDUCTION OF REMISSION IN AN INTENSIVE CHEMOTHERAPY PROTOCOL IN MEXICO" @default.
• W2951453112 doi "https://doi.org/10.1097/01.hs9.0000565236.08257.af" @default.
• W2951453112 hasPublicationYear "2019" @default.
• W2951453112 type Work @default.
• W2951453112 sameAs 2951453112 @default.
• W2951453112 citedByCount "0" @default.
• W2951453112 crossrefType "journal-article" @default.
• W2951453112 hasAuthorship W2951453112A5019994404 @default.
• W2951453112 hasAuthorship W2951453112A5044384633 @default.
• W2951453112 hasAuthorship W2951453112A5061048634 @default.
• W2951453112 hasAuthorship W2951453112A5064564382 @default.
• W2951453112 hasAuthorship W2951453112A5069814716 @default.
• W2951453112 hasAuthorship W2951453112A5081488322 @default.
• W2951453112 hasAuthorship W2951453112A5088239923 @default.
• W2951453112 hasAuthorship W2951453112A5091049255 @default.
• W2951453112 hasBestOaLocation W29514531121 @default.
• W2951453112 hasConcept C120665830 @default.
• W2951453112 hasConcept C121332964 @default.
• W2951453112 hasConcept C126322002 @default.
• W2951453112 hasConcept C143998085 @default.
• W2951453112 hasConcept C194409129 @default.
• W2951453112 hasConcept C2776611710 @default.
• W2951453112 hasConcept C2776694085 @default.
• W2951453112 hasConcept C2778368355 @default.
• W2951453112 hasConcept C2780401358 @default.
• W2951453112 hasConcept C2911091166 @default.
• W2951453112 hasConcept C61511704 @default.
• W2951453112 hasConcept C71924100 @default.
• W2951453112 hasConcept C88879693 @default.
• W2951453112 hasConcept C90924648 @default.
• W2951453112 hasConceptScore W2951453112C120665830 @default.
• W2951453112 hasConceptScore W2951453112C121332964 @default.
• W2951453112 hasConceptScore W2951453112C126322002 @default.
• W2951453112 hasConceptScore W2951453112C143998085 @default.
• W2951453112 hasConceptScore W2951453112C194409129 @default.
• W2951453112 hasConceptScore W2951453112C2776611710 @default.
• W2951453112 hasConceptScore W2951453112C2776694085 @default.
• W2951453112 hasConceptScore W2951453112C2778368355 @default.
• W2951453112 hasConceptScore W2951453112C2780401358 @default.
• W2951453112 hasConceptScore W2951453112C2911091166 @default.
• W2951453112 hasConceptScore W2951453112C61511704 @default.
• W2951453112 hasConceptScore W2951453112C71924100 @default.
• W2951453112 hasConceptScore W2951453112C88879693 @default.
• W2951453112 hasConceptScore W2951453112C90924648 @default.
• W2951453112 hasIssue "S1" @default.
• W2951453112 hasLocation W29514531121 @default.
• W2951453112 hasLocation W29514531122 @default.
• W2951453112 hasOpenAccess W2951453112 @default.
• W2951453112 hasPrimaryLocation W29514531121 @default.
• W2951453112 hasRelatedWork W1561150073 @default.
• W2951453112 hasRelatedWork W1998618181 @default.
• W2951453112 hasRelatedWork W1999020667 @default.
• W2951453112 hasRelatedWork W2094973406 @default.
• W2951453112 hasRelatedWork W2134306396 @default.
• W2951453112 hasRelatedWork W2360260519 @default.
• W2951453112 hasRelatedWork W2398926664 @default.
• W2951453112 hasRelatedWork W2415666441 @default.
• W2951453112 hasRelatedWork W2954897945 @default.
• W2951453112 hasRelatedWork W4244624038 @default.
• W2951453112 hasVolume "3" @default.
• W2951453112 isParatext "false" @default.
• W2951453112 isRetracted "false" @default.
• W2951453112 magId "2951453112" @default.
• W2951453112 workType "article" @default.