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- W2951461908 abstract "We herein, report the first total synthesis of Dermacozine A and B in moderate to high yields from a commercially available methyl 2-bromo (or chloro)-3-nitrobenzoate in an atom efficient route. The key carbon–nitrogen and carbon-carbon bond forming reactions involve inter and intra-molecular Pd (0) catalyzed N-arylations and regioselective Friedel-Crafts benzoylation respectively. Nitrile group was used as a masked carboxylic group to differentially functionalize two carboxylic acids to achieve Dermacozine C." @default.
- W2951461908 created "2019-06-27" @default.
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- W2951461908 date "2016-08-01" @default.
- W2951461908 modified "2023-09-24" @default.
- W2951461908 title "ChemInform Abstract: Synthetic Studies on Dermacozines: First Synthesis of Dermacozines A, B and C." @default.
- W2951461908 cites W2364289894 @default.
- W2951461908 doi "https://doi.org/10.1002/chin.201636191" @default.
- W2951461908 hasPublicationYear "2016" @default.
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