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- W2951482937 abstract "The reactions of isatin with cyclic ketones, viz camphor (dl, Mp 174–181°C, specific rotation −1.5° to +1.5°) available from s. d. fine- CHEM LTD and menthone (I, Bp 207°–210° C, density 0.893 g/mL) isolated from peppermint oil, in refluxing ethanol in the presence of t-BuOK afforded the corresponding indolylidene compounds (3a) and (3b) (a mixture of stereochemical isomers E and Z in both the cases) respectively, all obtained as racemates. Cyclocondensation of (3a) and (3b) with thiourea, urea, ethylenediamine and o-phenylenediamine afforded new spiro (4a,b-7a,b) and condensed systems (4a',b'-7a',b') respectively, whereas with 2-aminopyridine spiro compounds exclusively were obtained (8a,8b). All the new spiro and condensed systems generated have been isolated as racemates and evaluated for their antimicrobial activity." @default.
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- W2951482937 date "2008-11-01" @default.
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- W2951482937 title "Synthesis of some indole based spiro and condensed heterocycles as potential biologically active agents" @default.
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- W2951482937 doi "https://doi.org/10.1002/jhet.5570450634" @default.
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