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- W2951531901 abstract "Abstract The utilization of water as solvent and indium trichloride as promoter for the three-component combinatorial synthesis of a variety of bioactive pyrimidine and pyrazole derivatives (2–10) from aldehydes, 1,3-dicarbonyl compounds, and electron-rich amino heterocycles like 6-amino-1,3-dimethyl uracil and 3-methyl-1-phenyl-1H-pyrazol-5-amine catalyzed by indium trichloride under reflux has been studied. A new class of pyrimidine derivatives (2) has also been synthesized and the structure was confirmed by single crystal X-ray analysis. The reactions are environmentally benign, reaction product could be isolated easily and the catalyst could be recycled, which makes it an appealing synthetic protocol." @default.
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- W2951531901 date "2012-06-01" @default.
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- W2951531901 title "Aqua mediated indium(III) chloride catalyzed synthesis of fused pyrimidines and pyrazoles" @default.
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- W2951531901 doi "https://doi.org/10.1016/j.tetlet.2012.04.001" @default.
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