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- W2951532783 abstract "Densely substituted cyclopropanol and cyclopropylazole derivatives with three stereogenic carbons in the small cycle are obtained via a highly diastereoselective formal nucleophilic substitution of bromocyclopropanes. The chiral center at C-2 in bromocyclopropane dictates the configuration of the other two stereocenters that are successively installed via a sterically controlled addition of a nucleophile, followed by a thermodynamically driven epimerization of the resulting enolate intermediate." @default.
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- W2951532783 date "2013-11-21" @default.
- W2951532783 modified "2023-09-25" @default.
- W2951532783 title "Dual Control of the Selectivity in the Formal Nucleophilic Substitution of Bromocyclopropanes en Route to Densely Functionalized, Chirally Rich Cyclopropyl Derivatives" @default.
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- W2951532783 doi "https://doi.org/10.1021/ol4027792" @default.
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