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- W2951546711 abstract "Abstract Synthetic routes to vicinal -6-(6-Cl-3-pyridyl)- and distal -5-(6-Cl-3-pyridyl)-2-azabicyclo-[2.2.0]hexane analogs of the potent nicotinic receptor agonist epibatidine are described. Both exo -regioisomers are available from a readily available 2-azabicyclo[2.2.0]hex-5-ene by way of stereoselective reductive Heck addition of the 6-Cl-3-pyridyl moiety. Stereochemical inversion of the 6- and 5-aryl groups provides entry to the endo isomers." @default.
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- W2951546711 date "2000-11-01" @default.
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- W2951546711 title "Synthesis of 5- and 6-(6-Chloro-3-pyridyl)-2-azabicyclo[2.2.0]hexanes. Epibatidine Analogs" @default.
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- W2951546711 doi "https://doi.org/10.1016/s0040-4020(00)00896-6" @default.
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